Protein Alignment Nepl5 and nep-22

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 811
• Identity: 156/811 - (19%)
• Similarity: 271/811 - (33%)
• Gaps: 250/811 - (30%)

  Fly    37 AEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSL-RDRDWTRDRQRYQGQMLPTDTLGLID-- 98
            |..|.:.:|....||::||.:.|..: :|..:...| |.|..|.|:.:..........|..||
 Worm    72 ANYLLNGLDDTVDPCQDFYAFTCNKF-LQNTDLQKLGRSRLGTYDQAQVDVYSEIVAALSKIDVT 135

  Fly    99 HSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ------- 156
            .:...|.|    |..:::||              :||.          .|..|::.|.
 Worm   136 STTTSKTE----RITKAAFE--------------TCKN----------NLASPADKTAVVYAEIT 172

  Fly   157 -----WPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPS------ 210
                 .|..|...:.....|:.. |::......|.|........:.|....::|...|.
 Worm   173 SLFGGVPFFGEPLKTNVDYWMVA-GQIEQKHAVGTLTYTIASSDYKDHTKNALYTGPPGLSLARD 236

  Fly   211 -----------RQETQPMGEGAMIELLLDIGQTKRTANAL---ARQVDDFERKLHRLQELEDDEG 261
                       .|....:.:  ::....:..:....|:||   |::|.:||      .::.....
 Worm   237 FYVKPQYIAEVNQRVSDVND--LLTAFANAAKKNVGADALLAAAQEVVNFE------VQIAMASW 293

  Fly   262 PREMQLGYLDSYLP-----------QLRWLSFMRQV--RIDSELDLRSTLIIENIP-YLRALSDL 312
            |.::...|...|.|           .:.|.|::.|:  .:.|:.|..:..|:...| |...|:.:
 Worm   294 PDDLLRNYQQQYNPYNIASATTAYRAINWKSYLGQLFHGVASDADQANYNIVVTEPSYFAWLNSV 358

  Fly   313 MESESPDT--VCSYIMLKWLA----------------------------FLKQQGPAD------- 340
            .:.::.::  |.:|::.:.||                            .:|:.|..:
 Worm   359 FDGKTSNSTVVANYMIAQLLADESDFINPATAKVSSDTNYIHYALRNGRGIKKIGKREYRMADLD 423

  Fly   341 -ISRGECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVR------------------- 385
             ||.| |:..|...||..:.::            ||.|..:|.||:
 Worm   424 GISEG-CMDLLTAYMPYGTGYV------------YVKSKSERNKVQADVKDQTTLIINNFQGMID 475

  Fly   386 -------FGQILAENRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDV--EQYHVRIDL---SG 438
                   |.:..|.|:   |..||    :.........|.|......|.  :.|...|||   ..
 Worm   476 SLNWMDTFSKNRAHNK---SDSLV----KNFGWPEAMFGDFNDFTTVDAYNQDYASIIDLYTKDK 533

  Fly   439 HSFYGNQLVLLRQRVEANHDLLYINV-------TNFANSTGSNLSYLSESWEASNSSPLYVRPRN 496
            :..|| ...:|::.:|...   :..:       |||..|..     :..:|        |...||
 Worm   534 NDIYG-IFAVLKKGMEVRE---FFRIMGEPADRTNFLQSPA-----MVNAW--------YQPERN 581

  Fly   497 LVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDY-------DAMGNIMGPVEE 554
            .:..|:.....|.::.|.......|..|....|||.||:|..|:.:       |...|..|.: :
 Worm   582 SITFPYAAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEGVQFGFNGELTDCSWNKCGWM-D 645

  Fly   555 IGASRQFRQGLQCLQQQMAT--------------GSKWIDEKLADFVALRLAYETF--------F 597
            ..:|..|....||:..|.:|              |:....|.:||....:.||.::        .
 Worm   646 TNSSSGFIDMAQCVVTQFSTQCCPEKTGNIHCANGATTQGENIADLGGQQAAYRSYRQYVATTRK 710

  Fly   598 GVRDKREPRDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHL-------KHAADELRVMQ 655
            ||   .|.|.|.|..::..|:|:||:...:|        ..||:|:|       .|:..:.|..|
 Worm   711 GV---EEDRLPGLENYTPNQIFWITYGYSWC--------MKQSDANLVHQLLTNPHSPAQCRTNQ 764

  Fly   656 TLANFEEFSREFGCDKKAKM--QASQRCRIW 684
            .:.:..||.::|||.:.:.|  :.|.||::|
 Worm   765 VMQDIPEFGKDFGCVRGSPMYPEPSGRCKVW 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	153/804 (19%)
		GluZincin	48..682	CDD:301352	151/796 (19%)
nep-22	NP_509528.1	PepO	76..795	CDD:226118	153/805 (19%)
		M13	83..793	CDD:189000	151/796 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920