Protein Alignment Nepl5 and nep-23

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 738
• Identity: 148/738 - (20%)
• Similarity: 268/738 - (36%)
• Gaps: 202/738 - (27%)

  Fly    36 LAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLI-DH 99
            ||.||.:|.|..|.||:||||..||     :|.:|||:.                    ||. .|
 Worm    84 LAHQLHNYHDPSADPCDNFYQSVCG-----KQHEHSLKS--------------------GLAKKH 123

  Fly   100 SVNRKL--ELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ------ 156
            .:.|.|  |.:..|:...:.:|::    :||.::..|        .||.:....|:..|
 Worm   124 LILRNLIRETITNRKVTPTSKSEN----EMRKFHGIC--------SKYQRANSSSDIAQQALRDI 176

  Fly   157 ---------WPSVGRGWRPERFDWITTLGRL-----RLHGLNGVLL--REEVLPRWDD-SRNYSI 204
                     ||:..|.|....|:....|..|     |..||..:..  |:::|...:: .||||
 Worm   177 FRDVQSIGSWPAGSRNWNESDFNLNEMLNNLVKLGQRNFGLFQISFKYRDQLLISAEEHRRNYS- 240

  Fly   205 YVNKPSRQETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQELEDDEG-------- 261
                    :.:|        .:|:|.:|    |.|   |.|      |:|.|:|.||
 Worm   241 --------KLEP--------TILNIFET----NGL---VPD------RIQLLKDLEGFASLEALL 276

  Fly   262 --------PREMQLGYLDSYLPQLRWLSFMRQV------RIDSELDLRSTLI------IENIPYL 306
                    ..:|:...||..:|.:.::..::.:      .:..:::|:::::      .||:
 Worm   277 KNHYYLDNMDKMKPAVLDDLVPSVDFMGLVKAMISPGKEHLMPKIELKTSVLNQTLFNDENM--- 338

  Fly   307 RALSDLMESESPDTVCSYIM-------LKWLAF--LKQQGPADISRGECVAALRRAMPLASSWLV 362
             .|..::......|:.:|::       |..|.|  ..|:|      ..|...:...:|.||..:.
 Worm   339 -NLEAIILDTPKRTLANYLIFNFIDSSLDHLVFETTSQKG------NTCEDKVITYLPRASLRVF 396

  Fly   363 GQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMGF--------- 418
            .:.:.|.|:...::.|.::.::.. ..|.:|...|......:...|:.|:...:|:
 Worm   397 IRNYVDKENRDLITQLAEKTRIAL-HTLVQNSTWLKAESKQLALDKINAMGKMIGYPDFFEPPGT 460

  Fly   419 ----FQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLS 479
                |:...::..:.|:..::.....|...::....:....:.||....:..:....|:.|::|:
 Worm   461 LDGMFKNLNLDSSDTYYTALNKLERYFVEQKMDYFAEETPLDPDLRVFEMNAYYYIPGNQLNFLA 525

  Fly   480 ESWE---ASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMD 541
            ..::   ..::.|.||                    ||      |:.|.::.||:.|.|....:.
 Worm   526 PFFDDPMFDSTYPDYV--------------------NI------AMSGNIIGHEMGHAFGPHAIL 564

  Fly   542 YDAMGN--IMGPVEEIGASRQFRQGLQCLQQQMA-----------TGSKWIDEKLADFVALRLAY 593
            ....|.  .|.| ||:.   ::....|||..|.:           .|.|.|||.:||.:...:::
 Worm   565 RTVRGREVWMKP-EELA---EYESRAQCLANQYSEYDDPDFGRVFDGGKVIDELVADNIGREVSW 625

  Fly   594 ETFFGVRDKREPRDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLA 658
            :.|..:......|......:...||:|...|...|  ||......:......|.....||....|
 Worm   626 KMFKSLDLTNATRIIGFEDYDIDQLYFRVGALTHC--TPHAMRDLKGSIESSHPRKAFRVNGVYA 688

  Fly   659 NFEEFSREFGCDKKAKMQASQRC 681
            |..||:|.|.|...:.|...::|
 Worm   689 NLPEFARAFNCPTGSPMNPRKKC 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	144/732 (20%)
		GluZincin	48..682	CDD:301352	142/726 (20%)
nep-23	NP_503004.2	M13	96..711	CDD:189000	141/724 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920