Protein Alignment Nepl5 and nep-26

DIOPT Version :9

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 816
• Identity: 169/816 - (20%)
• Similarity: 281/816 - (34%)
• Gaps: 220/816 - (26%)

  Fly     1 MLKLSLVAWLIFSLA----WRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGN 61
            :|.:.|...|.|::|    ::|.|....:.       .|.|.:|...:|....||:||||:|||.
 Worm    80 VLVIFLFVTLSFAIACFLYYQTLPCTSEEC-------VMTASRLLKRVDQSVEPCDNFYQFACGG 137

  Fly    62 WQIQQ-----------------------QEQHSLRDRDW-------TRDRQRYQGQMLPTDTL-- 94
            |..|.                       |..|.:.|..:       .|...:...|.:.||||
 Worm   138 WINQSVNLKYDSWNTLYETQRTAHDQIVQAMHKINDGSYPLPTNAGERAAAKMYEQCMDTDTLEQ 202

  Fly    95 ----------------------GLIDHSVNRKLELLLRRRNESSFESDSSILEQMR-----LYYR 132
                                  |.::...:.::||....:....||.:..||....     |::.
 Worm   203 TGLHLWERFVDELGGWMPELKNGALEQEESFEIELDEDEKKRRRFEIEDIILSAFNYSVFPLFWA 267

  Fly   133 SCKRLKPYNLKKYLQLLPPSNSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWD 197
            ..: :...|.|::|..:    ..|.|.:   ..||::.:                 .:|:.|
 Worm   268 GVE-VNYLNSKEHLITI----YEQLPIL---LAPEKYHY-----------------NKELTP--- 304

  Fly   198 DSRNYSIYVNKPSRQETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQEL---EDD 259
             ...|......|..:..|.:||  .:..:|....|......:...:...|.::......   |..
 Worm   305 -EMIYGKMEGPPVTRALQQVGE--ELSAVLGFDSTDEKVRMMIANMIYLEYQITMAGSTFYKEKK 366

  Fly   260 EGPREMQLGYLDSYLPQLRWLSFMRQVRIDSELDLRSTLIIEN----IPYLRALSD-LMESESPD 319
            |....:.|..|....|.:.|..|:.:: :...|.....:.::.    ||.|.|:.: |.:|.|..
 Worm   367 ERYTVVMLRELQEIAPAINWHYFLSRL-VGENLSHSEPIALKTGTQWIPILSAIVEKLKQSRSGV 430

  Fly   320 TVC-SYIMLK------------------WLAFLKQQGPADISRGECVAALRRAMPLASSWLVG-- 363
            .|. :|:..|                  |:|.....|.|...:..||..|....||:...::.
 Worm   431 AVLKNYVKWKTIMFHLAYASPKCRDGLLWMAVSLYSGAASQRKEFCVLRLSGIFPLSLPSILRKI 495

  Fly   364 -------------QQFSDPESESY-----VSSLFQRLKVRFGQILAENRMR----LSPPLVHILQ 406
                         |..:|...|.|     .|:||...:.|...|...|.|.    ....:....:
 Worm   496 DGIDHTEKNVKAVQNIADRIQEKYEEMVRSSNLFSDRETRENVIDKVNNMTKFIGFPDAMRSDYE 560

  Fly   407 QKLRAVRLQMGFFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANST 471
            .:..||||....|.:            :.|...|.|..:|..||..|:
 Worm   561 MEKEAVRLHDTLFWS------------MVLGSSSVYKERLQRLRLPVD----------------- 596

  Fly   472 GSNLSYLSESW---EASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAH 533
                   ..||   ..:.|.|.:...||||.:|...|:||....:......:|.:|.::.|||.|
 Worm   597 -------PRSWVDTRPAISVPAHNYERNLVQIPFDSLRLPYADEHQLDFANYAGIGTIIGHELTH 654

  Fly   534 GFDMLGMDYDAMGNIMGPVEEIG------ASRQFRQGLQCLQQQ---------MATGSKWIDEKL 583
            .|       |..|.:.||...:|      :.|:|:...||..:|         |....:.:.|.:
 Worm   655 AF-------DGQGKLHGPTGNLGVWWSTDSIREFKAREQCFVKQYAGLMDSHDMNAAKEGLYENI 712

  Fly   584 ADFVALRLAYETFFGVRDKREPRDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAA 648
            ||.|.|::|||.:....::...|.|.|.::||.||||:.:.|.:|      :.||:|.....|..
 Worm   713 ADQVGLKVAYEAWKSNGNQNSGRMPGLEKYSQDQLFFLAYTQGWC------ALRSKSYKLQPHME 771

  Fly   649 DELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684
            :.:|::.:|.|..||:..:.|..::.|....:|.||
 Worm   772 ERIRMLGSLQNSPEFASAWKCSSESFMNPPDKCSIW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	157/769 (20%)
		GluZincin	48..682	CDD:301352	155/761 (20%)
nep-26	NP_001022540.1	PepO	111..807	CDD:226118	160/776 (21%)
		M13	124..805	CDD:189000	155/761 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020