Protein Alignment Nepl5 and nep-3

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 154/696 - (22%)
• Similarity: 261/696 - (37%)
• Gaps: 178/696 - (25%)

  Fly    36 LAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHS 100
            |..||.::.|....|||||||.|||.:     .:|::.|...|..:|:.
 Worm    70 LVHQLLNFQDPSVDPCENFYQAACGKY-----NEHNVIDGSRTAQKQQI---------------- 113

  Fly   101 VNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ--------- 156
            |.|.:...|.:...|:.:|::|    |:|.|..||..|.      :::|...|..|
 Worm   114 VKRLIRDFLHKNQSSTSKSENS----MKLLYEKCKEAKT------IKVLGNQNLLQEIFMNIQKI 168

  Fly   157 --WPSVGRGWRPERF---DWITTLGRLRL--HGLNGVLLREEVLPRWDDSRNYSIYVNKPSRQET 214
              ||.:...|..::|   :.:.:|.||.:  .|...:::..:.......:||:      |:|
 Worm   169 GSWPVLDENWDGKKFNLNEMLLSLIRLGVSNFGFFEIIISSDAFVEIKPARNF------PTR--- 224

  Fly   215 QPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQELEDDEGPREMQLGYLDSYLPQLRW 279
                     |.|.||.......|.....:...|..|...:.|:     ||::
 Worm   225 ---------ENLSDIISKVFLGNGFQPNITAIENDLREYENLQ-----RELK------------- 262

  Fly   280 LSFMRQVRIDSELDLRSTLIIENIPYLRALSDLMESESPDTVCSYIMLKWLAFLKQQGPADISRG 344
             |..|.::......|.:.||..   ||::                :||::....::|
 Worm   263 -SLERLIQTTPNRSLVNYLIFN---YLKS----------------VMLEYKRLPEEQ-------- 299

  Fly   345 ECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKL 409
             |...:...:|.||:.:..|.|.|.|:..||:.:.:.:|:.|..::.|:.. |:.....:..||:
 Worm   300 -CEGVVIDFLPRASTRVFVQNFLDKENRKYVAGMIEDVKMGFIDMIQESTW-LNEESKKVAVQKV 362

  Fly   410 RAVRLQMGF-------------FQTEEIEDVEQYHVRIDLSGHSFYGNQ---LVLLRQRVEANHD 458
            :.::..:|:             |:...||..:.||. |......|...|   .|.....::....
 Worm   363 KNIKSMIGYPDFFEPPGTLDRSFKDLNIEQTDSYHT-IVRKIQKFTNEQCMEFVASEIPLDPRQP 426

  Fly   459 LLYINVTNFANSTGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVM 523
            :|:      ||:...|.::|:                  :|.|  :|..||:..........||:
 Worm   427 ILH------ANAFYQNTNFLA------------------ILAP--VLDDPIFDTTFPRYVNLAVI 465

  Fly   524 GFVLAHELAHGFDMLGMDYDAMG--NIMGPVEEIGASRQFRQGLQCLQQQ-----------MATG 575
            |.|||||:.|.||..|::||..|  .|....|:   |.::.:.|:||.:|           ...|
 Worm   466 GNVLAHEIGHAFDHTGINYDDAGQQRIWLTPED---SEEYGKRLRCLLRQHDEYDDPDFGRNLNG 527

  Fly   576 SKWIDEKLADFVALRLAYETFFGVRDKREPRDPLLPQFSQRQLFFITFAQFFCGR--TPVLSPRS 638
            ||.:.|..||...:..|:.||..:....|........|:..||:|.|.|..:|.:  |..|....
 Worm   528 SKTLHEISADRFGVEAAWRTFKKLDLSNESEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYAL 592

  Fly   639 QSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684
            |.|    |..:..||....||..:|:..|.|...:.|...::|.::
 Worm   593 QRE----HPTNNFRVNGIYANMPQFAETFNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	149/680 (22%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	149/679 (22%)