Protein Alignment Nepl5 and Eef1ece2

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_808810.1
• Gene: Eef1ece2 / 110599584
• MGIID: 6121518
• Length: 910
• Species: Mus musculus
• Alignment Length: 722
• Identity: 158/722 - (21%)
• Similarity: 284/722 - (39%)
• Gaps: 131/722 - (18%)

  Fly    36 LAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHS 100
            :|.::...:|....||::|||::||.|         :|.......|.|:       :|...:...
Mouse   247 VAGKILESLDRGVSPCQDFYQFSCGGW---------IRRNPLPNGRSRW-------NTFNSLWDQ 295

  Fly   101 VNRKLELLLRRRNESSFESDSSILEQMRLYYRSC---KRLKPYNLKKYLQLLPPSNSTQWPSVGR 162
            ....|:.||   ..::|.|.|....:.|.:|.||   :|::....|....|:.....  |...|
Mouse   296 NQAILKHLL---ENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGG--WNITG- 354

  Fly   163 GWRPERF--------------DWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPSRQE 213
            .|..:.|              .:.|..........|..:::.:....:..||:|  |:|:.:.::
Mouse   355 PWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDY--YLNRTANEK 417

  Fly   214 TQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRL-----QELEDDEGPREMQLGYLDSY 273
            ........|:||.:.:|....:.....:||.:.|.:|..:     |..::::...:|.:..|.:.
Mouse   418 VLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQAL 482

  Fly   274 LPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALSDLMESESPDTVCSYIMLKWLAFLKQQGP 338
            .|.:.||.|:..:....||.....:::....||:.:|:|:....|..:.:|::  |....|....
Mouse   483 APAVDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLI--WNLVQKTTSS 545

  Fly   339 ADISRGE-----------------------CVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQ 380
            .| .|.|                       |::....|:..|...|..:...|.:|:.....:..
Mouse   546 LD-QRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMIN 609

  Fly   381 RLKVRFGQILA-----ENRMRLSPPLVHILQQKLRAVRLQMGF----FQTEEIEDV-EQYHVRID 435
            .::..|.:.|.     :.:.||:      .::|..|:...:||    .:.:|::|| :.|.|..|
Mouse   610 EIRSAFEETLGDLVWMDEKTRLA------AKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSED 668

  Fly   436 LSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSP-----LYVRPR 495
                ||:.|.|                |:.||:....::......|.:..:.:|     .|:..:
Mouse   669 ----SFFQNML----------------NLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTK 713

  Fly   496 NLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQ 560
            |.::.|.|:||.|.:..|.........:|.|:.|||.|.||..|.:||..||:. |..:..:...
Mouse   714 NEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLR-PWWQNESLTA 777

  Fly   561 FRQGLQCLQQQMA---------TGSKWIDEKLADFVALRLAYETFFGVRDKREPRDPLLPQ--FS 614
            |:....|:::|.:         .|.:.:.|.:||...|:.||..:.....|.....| ||.  .:
Mouse   778 FQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQP-LPAVGLT 841

  Fly   615 QRQLFFITFAQFFCGRTPVLSPRSQSEAHL--KHAADELRVMQTLANFEEFSREFGCDKKAKMQA 677
            ..||||:.|||.:|.   |.:|.|..|..:  .|:....||:.||:|..:|.|.|||...:.|..
Mouse   842 NHQLFFVGFAQVWCS---VRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNP 903

  Fly   678 SQRCRIW 684
            .|.|.:|
Mouse   904 GQLCEVW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	154/706 (22%)
Eef1ece2	NP_808810.1	UbiG	46..>128	CDD:441829
		M13	259..908	CDD:341056	154/706 (22%)