Protein Alignment Nepl5 and ecel1

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 785
• Identity: 166/785 - (21%)
• Similarity: 303/785 - (38%)
• Gaps: 235/785 - (29%)

  Fly    23 CRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQ 87
            |::..|.....:.:...:    |....||.:||.:|||.|         ||......|:..|
 Frog    92 CQERKAFMRASKFITNNI----DPTISPCTDFYSFACGGW---------LRRHGIPEDKLIY--- 140

  Fly    88 MLPTDTLGLIDHSVNRKLELLL----RRRNESSFESDSSILEQMRLYYRSCKRLKPYN---LKKY 145
                .|:..|......|||.||    ||:::.|.|      .:::.:::||..::..:   .:..
 Frog   141 ----GTIAAIGEQNEEKLEHLLLQPVRRKHKGSAE------RKVKEFFKSCLNMRDIDRLGARPM 195

  Fly   146 LQL--------LPPSNSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNY 202
            ||:        ||....|||            |:...|  .:..|:....:...:....|| :|.
 Frog   196 LQVIEDCGGWDLPEDPRTQW------------DFNELL--YKTQGVYSTAVFFSMTVSLDD-KNS 245

  Fly   203 SIYVNKPSRQETQPMGEGAMI-ELLLDIGQTKRTANALARQ------------VDDFERK----L 250
            |.|:.:..:       :|..: |..|.:||.:.:...|...            |::.::|    |
 Frog   246 SRYIIRIDQ-------DGLTLPERTLYLGQDEESIKVLEAYKVFMQTILSLLGVENVQKKAEEIL 303

  Fly   251 HRLQEL------EDDEGPREMQ-------LGYLDSYLPQLRWLSFMRQV-----RIDSELDLRST 297
            |..|.|      |.|:..|::.       |..|....|.|.|.:.:.::     ..|.|:.:.:|
 Frog   304 HLEQHLSNITISEFDDMRRDISTMYNKVTLAQLQQITPHLNWKNLLNRIFHTNFPEDEEVVVLAT 368

  Fly   298 LIIENIPYLRALSDLMESESPDTVCSYIMLKWLAFLKQ--------------------QGPADIS 342
                  .|::.:|:::.|.....:.:|::.:.:..|.:                    :..|:::
 Frog   369 ------DYMQKVSEMIRSTPASVLHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGSEKQAELT 427

  Fly   343 RGECVAALRRAMPLASSWLVGQQFSDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHIL-- 405
            : .|:....:...:|...|..:::....|::.|..|.:.:|                   |||
 Frog   428 K-VCLTQANKHFGMALGALFVEEYFSSSSKAKVQQLVENIK-------------------HILDY 472

  Fly   406 ----------------QQKLRAVRLQMGF----FQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLR 450
                            ::||:.:.:.:|:    .|.|.::...::.|    :..:::.|.|..:|
 Frog   473 RLEELDWMDTETKQAAREKLKHMMVMIGYPDVLLQPESMDKEYEFEV----NEKTYFKNILNSIR 533

  Fly   451 -------QRVEANHDLLYINVTNFANSTGSNLSYLSESW----EASNSSPLYVRPRNLVLVPHGL 504
                   :|:....|                    ..:|    :|.|:  .|:..:|.::.|.|:
 Frog   534 YSIKMAVRRIRQEVD--------------------KSAWLLPPQALNA--YYLPNKNQMVFPAGI 576

  Fly   505 LQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVE---EIGASRQFRQGLQ 566
            ||..::..:......:..:|.::.|||.||:|..|..|||.||   |::   |...|: |.:..:
 Frog   577 LQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDANGN---PIQWWTEDSYSK-FLKKAE 637

  Fly   567 CL---------QQQMATGSKWIDEKLADFVALRLAYETF-FGVRDKREPRDPLLP--QFSQRQLF 619
            |:         ..|...|...:.|.:||...|:|||..: ..||| ..|..| ||  :::..|||
 Frog   638 CIVDLYENFTVYNQRVNGRTTLGENIADLGGLKLAYYAYQKWVRD-NGPERP-LPRLKYTHDQLF 700

  Fly   620 FITFAQFFCGRTPVLSPRSQSEAHL-----KHAADELRVMQTLANFEEFSREFGCDKKAKMQASQ 679
            ||.|||.:|     :..|||| .:|     |||.:..|||.:::.||||.|.|.|.:.:.|....
 Frog   701 FIAFAQNWC-----IKRRSQS-IYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNSPMNPVH 759

  Fly   680 RCRIW 684
            :|.:|
 Frog   760 KCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	161/756 (21%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	161/756 (21%)