Protein Alignment Nepl5 and ece2

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 734
• Identity: 159/734 - (21%)
• Similarity: 284/734 - (38%)
• Gaps: 155/734 - (21%)

  Fly    36 LAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHS 100
            :|.::...:|....||::||||:||.|    ..::.|.|     .|.|:       :|...|...
 Frog   103 VAGRILDSLDRGIDPCQDFYQYSCGGW----MRRNPLPD-----GRSRW-------NTFNSIWDQ 151

  Fly   101 VNRKLELLLRRRNESSFESDSSILEQMRLYYRSC---KRLKPYNLKKYLQLLPPSNSTQWPSVGR 162
            ....|:.:|   ..::|.|.|....:.:.:|.||   :|::....|....|:.....  | ::..
 Frog   152 NQAILKHIL---ENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGG--W-NISG 210

  Fly   163 GWRPERFDWI--TTLGRLRLHGLNGVLLREE----------------VLPRWDDSRNYSIYVNKP 209
            .||.|.|..:  |..|..|......|.:..:                .||    ||:|  |:||.
 Frog   211 NWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLP----SRDY--YLNKT 269

  Fly   210 SRQETQPMGEGAMIELLLDIGQ----TKRTANALARQVDDFERKLHRLQELEDDEGPRE-----M 265
            :..:..    .|.::.::.:|:    :..:.:....|:.:||..|..|...:|:....|     |
 Frog   270 ANGKVL----DAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRM 330

  Fly   266 QLGYLDSYLPQLRWLSFMRQVRIDSELDLRST--LIIENIPYLRALSDLMESESPDTVCSYIMLK 328
            .:..|.|..|...|:.::....  |.|||..|  :::....||:.:|:|:.:..|..:.:|::
 Frog   331 TISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELVNNTDPMLLNNYLV-- 391

  Fly   329 WLAFLKQQGPADISRGE-----------------------CVAALRRAMPLASSWLVGQQFSDPE 370
            |....|.....| ||.|                       |::.....:..|...|..:...|..
 Frog   392 WNLVQKMSSSLD-SRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKN 455

  Fly   371 SESYVSSLFQRLKVRF-----GQILAENRMRLSPPLVHILQQKLRAVRLQMGF----FQTEEIED 426
            |::....:...::..|     |....:.:.|      ...::|..|:...:||    ..|:|:::
 Frog   456 SKNIAEQMISEIRDAFELTLGGLTWMDEKTR------RAAKEKADAIYDMIGFPDFILDTKELDE 514

  Fly   427 VEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYL------SESWEAS 485
            |              |..        .|.:.|..:.|:.||.|.:...::..      .|.|..:
 Frog   515 V--------------YDG--------FEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMT 557

  Fly   486 --NSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNI 548
              ..:..|:..:|.::.|.|:||.|.:............:|.|:.|||.|.||..|.:||..||:
 Frog   558 PQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNL 622

  Fly   549 MGPVEEIGASRQFRQGLQCLQQQ---------MATGSKWIDEKLADFVALRLAYETF--FGVRDK 602
            . |..:..:...|:...:|:..|         ...|.:.:.|.:||...|:.||..:  :.|:..
 Frog   623 R-PWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHG 686

  Fly   603 REPRDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHL--KHAADELRVMQTLANFEEFSR 665
            .|.:.|.: ..:..||||:.|||.:|.   |.:|.|..|..:  .|:..:.||:.||:|.::|:.
 Frog   687 EEKQLPGV-GLTNNQLFFVGFAQVWCS---VRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAE 747

  Fly   666 EFGCDKKAKMQASQRCRIW 684
            .|.|.|...|...:.|.:|
 Frog   748 HFNCPKGTPMNPGKHCDVW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	155/718 (22%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	155/717 (22%)