Protein Alignment Nepl5 and ece1

DIOPT Version :10

• Sequence 1: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_031762312.1
• Gene: ece1 / 100485607
• XenbaseID: XB-GENE-1014218
• Length: 782
• Species: Xenopus tropicalis
• Alignment Length: 774
• Identity: 170/774 - (21%)
• Similarity: 297/774 - (38%)
• Gaps: 169/774 - (21%)

  Fly     1 MLKLSL-VAWLIFSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQI 64
            :|.|.| :..|..||.:|.:...|    ..:|...:.:..|:| :|..|.||::||||:||.|
 Frog    88 LLSLGLFMCLLALSLQYRNSHRVC----LSESCISVTSSILRS-LDRSADPCQDFYQYSCGGW-- 145

  Fly    65 QQQEQHSLRDRDWTRDRQRYQGQMLPT-----DTLG-LIDHSVNRKLELLLRRRNESSFESDSSI 123
                               .:|..:|.     .|.. |.:|:......||    ..|:.|::|:.
 Frog   146 -------------------IKGNPVPDGHSRWGTFNELWEHNQATMKHLL----ENSTIETNSTA 187

  Fly   124 LEQMRLYYRSC---KRLKPYNLKKYLQLLPPSNSTQWPSVGRGWRPERFDWITTLGRLRLHGLNG 185
            ..:.:.|:::|   .:::....|....|:.....  |...| .|..:.|.  .||..:..|....
 Frog   188 ERKAQRYFQACMNETKIEELGAKPLQDLIQKLGG--WAITG-PWDRDNFQ--ETLQLVTAHYRTS 247

  Fly   186 VLLREEVLPRWDDSRNYS-----------------IYVNKPSRQETQPMGEGAMIELLLDIGQTK 233
            ......|..   ||:|.:                 .|:||...::........||:|.:.:|..:
 Frog   248 PFFSVFVSA---DSKNSNSNVIQIDQSGLGLPSREFYLNKTENEKVLTGYLNFMIQLGVLLGGAE 309

  Fly   234 RTANALARQVDDFERKLHRL---QELEDDEGP--REMQLGYLDSYLPQLRWLSFMRQVRIDSELD 293
            .:.....:::.|||..|..:   ||...||..  .:|..|.|...:|.:.|:.|::.|.....::
 Frog   310 NSTREQMQEILDFETTLANITIPQEKRRDEEQIYHKMAAGELKDLVPAVDWMPFLQTVFYPVAIN 374

  Fly   294 LRSTLIIENIPYLRALSDLMESESPDTVCSYIM----LKWLAFLKQ------QGPADISRGE--- 345
            ....:::....||.|:|.|:.|.....:.:|:|    .|..:||.|      :...::..|.
 Frog   375 ESEPVVVYAKEYLVAVSGLINSTDKRILNNYMMWNLVRKASSFLDQRFQDAEEKLMEVMYGTKKT 439

  Fly   346 -------CVAALRRAMPLA-SSWLVGQQFSDPESESYVSSLFQRLKVRFGQILA-------ENRM 395
                   |::.....:..| .:..|...|:: .|:.....:.:.:|..|.:.|:       |.|
 Frog   440 CLPRWKFCISDTDNNLGFALGAMFVKATFAE-NSKLQALKMIKEIKAAFEENLSTLTWMDDETR- 502

  Fly   396 RLSPPLVHILQQKLRAVRLQMGF----FQTEEIEDV-EQYHVRIDL---SGHSFYGNQLVLLRQR 452
                   ...::|..|:...:|:    ...:|::.| ..|:|..|.   :|..||
 Frog   503 -------RAAREKAEAIYDMIGYPNFIMDPKELDKVFNDYNVTSDFYFENGMRFY---------- 550

  Fly   453 VEANHDLLYINVTNF-ANSTGSNLSYLSESWEASNSSP---LYVRP-RNLVLVPHGLLQLPIWHR 512
                         || |..|...|.......:.|.:.|   .|..| :|.::.|.|:||.|.:..
 Frog   551 -------------NFSARVTADQLRKAPSKDQWSMTPPTVNAYYSPTKNEIVFPAGILQAPFYTS 602

  Fly   513 NISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQFRQGLQCLQQQM----- 572
            :.........:|.|:.|||.|.||..|.:||..||:. |..:..:...|::..:|:.:|.
 Frog   603 SSPTALNFGGIGVVMGHELTHAFDDQGREYDKDGNLR-PWWKNASVEAFKKQTECITEQYGNYTV 666

  Fly   573 ----ATGSKWIDEKLADFVALRLAYETFFG-VRDKREPRDPLLPQ--FSQRQLFFITFAQFFCGR 630
                ..|.:.:.|.:||...|:.||..:.. ||  :...:.|||.  .|..||||:.|||.:|
 Frog   667 NGEPVNGRQTLGENIADNGGLKAAYRAYKNWVR--KNGAEQLLPSLGLSNDQLFFVGFAQVWC-- 727

  Fly   631 TPVLSPRSQSEAHL-----KHAADELRVMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684
                |.|:...:|.     .|:....||:.:::|.:||:..|.|...:.|....:|.:|
 Frog   728 ----SVRTSESSHEGLITDPHSPSRFRVIGSVSNSQEFAEHFRCPPGSPMNPRNKCEVW 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl5	NP_609022.1	M13	48..682	CDD:341056	156/722 (22%)
ece1	XP_031762312.1	M13	131..780	CDD:341056	156/722 (22%)