Protein Alignment Nepl4 and Nepl21

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 163/760 - (21%)
• Similarity: 287/760 - (37%)
• Gaps: 211/760 - (27%)

  Fly    19 SSVPVKANDPEQSCPYLGECNSTINQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGS---HT 80
            ::.|....|.:|..||:.|   .:.|.....:.|::|.:.:||.||||::||.::..:.:   ..
  Fly    27 AAAPTSEEDLKQDTPYMKE---LLRQAKTAEIESFMDQKADPCNDFYAFSCGNYKRINSALSMQV 88

  Fly    81 TATMISES---QINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAHYQSCIALEKPDLRRYIELLDR 142
            ..|.:.|:   .:||:    .|::|..|. ..:..|...||...|:||:.:::
  Fly    89 VTTGVFETLTKGLNRK----ILKMLNTPH-DSHDTPEDIKVKHFYESCLQIKE------------ 136

  Fly   143 DLLASLNSTHWMHLLAALGRYG-----YHGHYVQVEVRWYNATHHM--------IFLLPHNRHLN 194
                 ||||:...|...:..:|     ....:.:.:..|.|.|..|        ||.:..|:.|.
  Fly   137 -----LNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLA 196

  Fly   195 LSLTQDIYDALSQDGSSWPPLHQ-----------LQEQFRS------------------------ 224
            .:....||  |.|...   ||..           .::::|:
  Fly   197 SNTRNRIY--LGQQDF---PLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKEL 256

  Fly   225 ------LEQNLV---------RLAKPHSADDTFRNYSLDQIRTEVPGLHWDEALRTQLGRSVPG- 273
                  |.|.||         .|.:..:.|:..|.||        |.|..|..|...:|..:..
  Fly   257 IDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRRYS--------PTLDIDRLLFVSMGERISDQ 313

  Fly   274 ----NHVFQVDDLDAIEGLVEYLNTVDTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNC 334
                |:.:|       :.|||.:.......:..|...|.:...:|.|       ......:.:.|
  Fly   314 IYEYNNRYQ-------QNLVEVIKRTPKRTVANYIFFRLIWEFVETP-------SDSPEKQMKAC 364

  Fly   335 IRHMRRSVYLPMNYVYERSFYSRRRHADE---LVIHSVFQQLQSQLELRVQHN-AFNLSQDLVKS 395
            :...::  |...|  .:..||  ||:.:|   ..|.::::||:|.....::.: |.|..:...::
  Fly   365 VDLTKK--YFAKN--LDNMFY--RRYNNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRN 423

  Fly   396 L-QAKVHQMRINVGN-LPPNVTEQF---YWDSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSD 455
            | .||:..|.:.|.| ...|.||:|   ...||       |:.||     :.|.:|:      ..
  Fly   424 LAMAKLQAMTLEVNNYADDNFTEEFAELNLQSD-------DYVEN-----VRYTSLL------GA 470

  Fly   456 QEERDIWYSFNMHTPEFP----DNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWP-ALLYGDLA 515
            ::.|::     :|.|..|    ..:..||....:.|.|.||.:.::..:..::.:| |:::|.||
  Fly   471 KQMREM-----LHKPAKPFEAGSQLSYTPANILIENTIKVPVALLQPFYIWSDVYPNAIMFGTLA 530

  Fly   516 NTLGHEIMHAFDTDLVDYDAQGNLRNFSDQ------LGEVELYNGAVGCLNSSAVMLNERT---- 570
            :.:|||::|.||.....:|.:||.:::.|:      |...:.:....|......:.|.|.|
  Fly   531 SLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSE 595

  Fly   571 --SDVSGSRLAMQTY------------GGDWLT-------RSGNGRLYFLQFAHFFCGD------ 608
              :|..|.|||...|            |...:|       |....:|:|:.||..:|.|
  Fly   596 NIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPSVK 660

  Fly   609 ----EGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQC 649
                ..|| |..|..|:..:|....:|::.|.|..||.|..:::|
  Fly   661 ALQVSTDQ-HMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKC 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	154/720 (21%)
		GluZincin	59..649	CDD:301352	153/718 (21%)
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	156/727 (21%)
		M13	63..704	CDD:189000	153/719 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020