Protein Alignment Nepl4 and Nepl14

DIOPT Version :10

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 758
• Identity: 151/758 - (19%)
• Similarity: 274/758 - (36%)
• Gaps: 191/758 - (25%)

  Fly     5 LWTALLLLGSATCGSSVPVKANDPEQSCPYLGECNSTINQQHIDTLMSYVDSEKNPCEDFYAYAC 69
            ||...|...:...|..:|    .|.|.   :.:...|:.:.....:.|:|:...:||.|||||||
  Fly    14 LWLPHLQQNALVSGEDLP----PPFQR---IYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYAC 71

  Fly    70 GKWRAKHGSHTTATMISESQINRQYEDLFLQLLRNPSAPEYGYPM-FAKVLAHYQSCIALEKPDL 133
            |.|:        :|:..:.|:.:|.:...|.|:......|....: .||.|  ::||::.:....
  Fly    72 GNWK--------STLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKEL--FKSCVSAQAHQS 126

  Fly   134 RRYIELLDRDL-----LASLNSTHW------MHLLAALG----RYGYH---GHYVQVEVRWYNAT 180
            ::....|...:     ..::..:.|      .:.|:.||    |||..   |  ::|...:.|..
  Fly   127 QQQQHFLSEFINQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGMDILIG--LRVGYNYGNVN 189

  Fly   181 HHMIF------LLP-----HNRHLNLSLTQDIYDAL----SQDGSSWPPL-H----QLQEQFRSL 225
            .:.::      |:|     .||.   .:...||:.|    :.:..||..| |    :|.....|.
  Fly   190 ENSLYLSEPSTLIPTELCTRNRS---DIRDSIYEPLEHRVASELKSWLALGHDESARLAADILSF 251

  Fly   226 EQNLVRLAKPHSADD-------TFRNYSLDQIR--TEVPGLHWDEALRTQLGRSVPGNHVFQVDD 281
            |..|....|..|.:.       ...||:...:|  :....|..|..:|...|:.     :::...
  Fly   252 EHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQD-----IYKPVY 311

  Fly   282 LDAIEGLVEYLNTV---DTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVY 343
            :.|.|...:...||   :..|:..|.:.|.:|.|    :.||   :...:.|.|.|:...:..:.
  Fly   312 MAAPEYFRQLKRTVSAHNISLVANYIMYRAVSAL----NFPL---DDRPQLRKRECLERTKELLP 369

  Fly   344 LPMNYVYERSFYSRRRHADELVIHSVFQQLQSQLELRV-------------QHNAFNLSQDLVKS 395
            ..:..:|.|.|.:.....|   :.:::..|::.|...:             |....||...:...
  Fly   370 TALGELYARQFGTEDGRID---LDNLYDTLKTALRQSLGAEWLVEGTQRVGQEKLRNLKLQMPTY 431

  Fly   396 LQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSDQEERD 460
            .:..:.::::..||         ||.:.|: .:|  ..::..|:.|:...|.|..:.....|.|
  Fly   432 ERPVILKLQLERGN---------YWQNLRQ-LLG--VVQSQRNNRLFEEFLPAPTDPVEAYEAR- 483

  Fly   461 IWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHA 525
                  :........:|       :|..:..|      |.:|..:..|:.|..|...|..:::.|
  Fly   484 ------VRLRPVQRRLD-------MGLALLQP------PAYDPRYGHAIRYATLGVQLAQQLVMA 529

  Fly   526 FD-----TDLVDYDA-------QGNLRN--FSDQLGEVELYNGAVGCLNSSAVMLNERTSDVSGS 576
            ||     ..|::.|.       |.::|:  |:.|   |:.|      |..:.....:..:|.:..
  Fly   530 FDDPHWSVGLLERDNWDGQTAWQYHIRSNCFARQ---VDNY------LRPNVSATTQLITDSAAI 585

  Fly   577 RLAMQTY---------GGDW--LTRS-------GNGRLYFLQFAHFFCG-DEGDQYHDSG----- 617
            .:|.:.|         ..|:  ||:.       .|..|:||.:|...|. :|.....:.|
  Fly   586 NVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQGTPEGY 650

  Fly   618 --SQRLNYA---------LGQVPQFAEVFRCHVGSGMTSADQC 649
              |.|.|:.         |....:||..|||.:||.|..|.:|
  Fly   651 LYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKC 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	140/702 (20%)
Nepl14	NP_651097.1	M13	60..693	CDD:341056	140/703 (20%)