Protein Alignment Nepl4 and Nepl11

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 671
• Identity: 145/671 - (21%)
• Similarity: 223/671 - (33%)
• Gaps: 190/671 - (28%)

  Fly    50 LMSYVDSEKNPCEDFYAYACGKWRAKHGSHTTAT-------MISESQINRQYEDLFLQLLRNPSA 107
            |..|:|:.|.||:|||.|.|     .|.::.:.|       ::.|:.: .|..|:.|||:.
  Fly    35 LEPYLDTSKQPCQDFYGYVC-----SHSANLSETGRQRFQSLLKETDV-AQLMDMELQLIN---- 89

  Fly   108 PEYGYPMFAKVLAHYQSCIALEKPDLRR----YIELLDRDLLAS--LNST-HWMHLLAALGRYGY 165
                   |.|.....:...||:...|.|    :..|....:.||  .|.| .|:.||
  Fly    90 -------FFKSCESGRGVEALKGSQLYRQSGGWPSLEPNKVNASQRTNQTQRWLGLL-------- 139

  Fly   166 HGHYVQVEVRWY-------NATHHMIFLLPHNRHLNL--SLTQDIYDALSQDGSSWPPLHQLQEQ 221
             |::.:|...::       .:...::.|.|.....|.  ...|.:.:.|...|......|....:
  Fly   140 -GYFHEVGAPYFFETSVTMQSNKRLVVLQPDGTRRNTLRKFEQRVGEVLQSFGIEQSRAHVTALE 203

  Fly   222 FRSLEQNLVRLAKPHSADD------------TFRNYSLDQIRTEVPGLHWDEALRTQLGRSVPGN 274
            ..|||::...:.|....:|            .|.|.||  ||     |.||...|..||...|
  Fly   204 VLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASL--IR-----LDWDGYFRKLLGGKTP-- 259

  Fly   275 HVFQVDD---LDAIEGLVEYL----NTVDTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGR 332
               |..|   :..:..||||.    ||....||| :....:|..:::...:.|:...:|
  Fly   260 ---QASDTIVVKQLPRLVEYFALLQNTSMVRLLN-WIWTDYLMDIVDADCHQLSETYAG------ 314

  Fly   333 NCIRHMRRSVYLPMNYVYERSFYSR--RRHADEL----VIHSVFQQLQSQLELRVQHNAFNLSQD 391
            :...|:.:.|  ..|.|.....||.  :.:.|:|    .|..:.:|...|....:.|...|..:
  Fly   315 DLYAHVVQRV--TANRVELAQMYSELGKAYTDQLGGSVWIDEISRQSSRQFLGNIMHTTLNGDE- 376

  Fly   392 LVKSLQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSDQ 456
               .|.|..|.:.:...:|..|:.:...:...||                        |.|.|.|
  Fly   377 ---RLDAAYHSILLGRRSLYRNLEKLRKFQRTRR------------------------LASHSAQ 414

  Fly   457 EERDIWYSFNMHTPEFPDNIDATPYFYCLG-NIIFVPYSYVKRPFFDANFWPALLYGDLANTLGH 520
            :.|.....|             .|....|| :.:..|.:|             ||.|:.
  Fly   415 QVRRYAQMF-------------APVNAFLGQHNLSTPLNY-------------LLLGEF------ 447

  Fly   521 EIMHAFDTDLV----DYDAQGNLRNFSDQLGEVELYNGAVGCLNSSAVMLNERTSDVSGSRLAMQ 581
                 |...||    ....||..|: ||......::...||...::..:|    ..:...|.|:.
  Fly   448 -----FSRSLVAAGSSSRTQGAWRS-SDSERRFAIFQQCVGKQTNAIDLL----LSLLAQRQALS 502

  Fly   582 TYGGDWL-TRSG-----------------NGRLYFLQFAHFFCGDE-GDQYHDSGSQRLNYALGQ 627
            .| |.|| |::|                 ..||:|:......|..| |....|...|..:..|..
  Fly   503 AY-GQWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQQDRKRQVTHATLRN 566

  Fly   628 VPQFAEVFRCHVGSGMTSADQ 648
            .|:|.|.|||..|..:...||
  Fly   567 SPEFLEAFRCRPGDVLYPQDQ 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	142/663 (21%)
		GluZincin	59..649	CDD:301352	141/662 (21%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	141/661 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910