Protein Alignment Nepl4 and Nepl9

DIOPT Version :10

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 739
• Identity: 134/739 - (18%)
• Similarity: 234/739 - (31%)
• Gaps: 260/739 - (35%)

  Fly    36 GECNSTINQQHIDTLMSYVDSEKNPCEDFYAYACGK--------------------------WRA 74
            |:..|.:.:.::..|:...:...:||:||||:|||.                          :.|
  Fly    39 GQFFSHLYKSNLQQLVKIKNDSMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFTA 103

  Fly    75 KHGSHTTATMISESQINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAHYQSCIALEKPDLRRYIEL 139
            :.|:..|   |....|::.|.:...:..||...|       .::.:|::..:. |.|.|.|:.|:
  Fly   104 EVGNFET---IPGRLISQLYTECRKREERNVFTP-------TRLTSHWERMLD-EIPFLARHKEV 157

  Fly   140 LD-----------RDLLASLNSTHWMHLLAALGRYGYHGHYVQVEVRWYNATHHMIFLLPHNRHL 193
            |.           |.|...||   |:.|.|.|..:|                      ||...|:
  Fly   158 LSSWPFLKHQWERRRLYGQLN---WIVLSAQLAAHG----------------------LPTLLHI 197

  Fly   194 NLSL---------------TQDIYDALSQ--DGSSWPPLHQLQEQFRSL------EQNLVRLAKP 235
            ..:|               ..|...:||.  :|........:..:.|.|      |..|||....
  Fly   198 YFALDTIYVSPMEELPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVRSLSQ 262

  Fly   236 HSADDTFR---------NYSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEY 291
            ::..:|.|         ..::|..:.....|::.|       ..:.|...|.: |::.|....|.
  Fly   263 NTRTNTSRPGEEQLLLDENTMDYFQQYFAALNFSE-------ERLVGARKFPL-DVEKITQAWEV 319

  Fly   292 LNTVDTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCI--------------------- 335
            |...:|.::..|.:                 |::.::.|..:|.
  Fly   320 LRHTETRIVYNYVM-----------------WQAREQLRYPDCYRVSEEFERLLHAEYWQWHVLR 367

  Fly   336 RHMRRSVYLPMNYVYERSFYSRRR-----------------HADELVIHSVFQ----------QL 373
            ||:.|.|.|....::...|...||                 ...||.:..:.|          :|
  Fly   368 RHLSREVALASYQLHTTRFQKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAENYLNITEL 432

  Fly   374 QSQLE-LRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRDFYENHL 437
            ....| |:::.|:|..:..:::..|.: |..      :.|.|.|:   |.::.....|.|....|
  Fly   433 NENYEGLKLEKNSFYANLLILRRAQLR-HSF------VSPYVDEE---DVNQPAYFLRHFLHFVL 487

  Fly   438 NSL---LYYYTLVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFY---CLGNIIFVPYSYV 496
            .||   .|:|.....||         :|....:       .:|...::.   ||....|..|
  Fly   488 LSLHRPTYHYYATHGLE---------LWRESRL-------LLDTDGHYTAMDCLERQSFQHY--- 533

  Fly   497 KRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQGNLRNFSDQLGEVELYNGAVGCLNS 561
                 ||...|  :|..|.:   |||...|..          .|:|...|.:...:
  Fly   534 -----DAKLAP--IYRPLGS---HEIAEIFQF----------YRSFQYSLTDYHFW--------- 569

  Fly   562 SAVMLNERTSDVSGSRLAM-QTYGGDWLTRSGNGRLYFLQFAHFFCGDEGDQYHDSGSQRLNYAL 625
                       :.|.|.|. :|:..|:...:.: |:.|...|...|..:.:.:    :.:||...
  Fly   570 -----------LQGERFAFAETFVLDYFGLNPH-RVLFYAVAQQLCNRQTEIF----AAQLNRGY 618

  Fly   626 GQVPQFAEVFRCHVGSGMTSADQC 649
            ..:|:|.|.|:|.....|....:|
  Fly   619 MNLPEFQEAFKCGAEKAMNPPSRC 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	130/714 (18%)
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	130/714 (18%)