Protein Alignment Nepl4 and Nepl5

DIOPT Version :10

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 164/723 - (22%)
• Similarity: 289/723 - (39%)
• Gaps: 169/723 - (23%)

  Fly    38 CNST-----INQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGSH------------------ 79
            |..|     :.:...:.|.||:|::..|||:||.||||.|:.:....
  Fly    23 CRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQ 87

  Fly    80 ---TTATMISESQINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAHYQSCIALEKPDLRRYIELLD 141
               |....:.:..:||:.|.|..:  ||.|:.|....:..::..:|:||..|:..:|::|::||.
  Fly    88 MLPTDTLGLIDHSVNRKLELLLRR--RNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLP 150

  Fly   142 RDLLASLNSTHWMHL-----------LAALGR---YGYHGHYVQVEV--RWYNATHHMIFLLPHN 190
            ..     |||.|..:           :..|||   :|.:|..::.||  ||.::.::.|::...:
  Fly   151 PS-----NSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVLLREEVLPRWDDSRNYSIYVNKPS 210

  Fly   191 RH--------------LNLSLTQDIYDALSQDGSSWP-PLHQLQEQFRSLEQNLVRLAKPHSADD 240
            |.              |::..|:...:||::....:. .||:|||    ||.           |:
  Fly   211 RQETQPMGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRLQE----LED-----------DE 260

  Fly   241 TFRNYSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEYLNTVDTLLLNRYSL 305
            ..|...|..:.:.:|.|.|...:|.           .::|         ..|:...||::.....
  Fly   261 GPREMQLGYLDSYLPQLRWLSFMRQ-----------VRID---------SELDLRSTLIIENIPY 305

  Fly   306 ARFLSHLLELPHNP-------LATW-----ESGQR--SRGRNCIRHMRRSVYLPMNYVYERSFYS 356
            .|.||.|:| ..:|       :..|     :.|..  ||| .|:..:||::.|..:::..:.|..
  Fly   306 LRALSDLME-SESPDTVCSYIMLKWLAFLKQQGPADISRG-ECVAALRRAMPLASSWLVGQQFSD 368

  Fly   357 RRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNV---TEQF 418
            ..   .|..:.|:||:|:.:....:..|...||..||..||.|:..:|:.:|......   .||:
  Fly   369 PE---SESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDVEQY 430

  Fly   419 YWDSDRRWSVGRDFYENHL----------NSLLYY-YTLVADLESSSDQEERDIWYSFNMHTPEF 472
            :...|..   |..||.|.|          :.|||. .|..|:...|:.....:.|.:.|
  Fly   431 HVRIDLS---GHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASN------ 486

  Fly   473 PDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQG 537
                 ::|.:....|::.||:..::.|.:..|......:..:...|.||:.|.||...:||||.|
  Fly   487 -----SSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMG 546

  Fly   538 NLRNFSDQLGEVELYNGAVGCLN----SSAVMLNERTSDVSGSRLAMQTYGG---------DWLT 589
            |:....:::|....:...:.||.    :.:..::|:.:|....|||.:|:.|         ..|.
  Fly   547 NIMGPVEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFGVRDKREPRDPLLP 611

  Fly   590 RSGNGRLYFLQFAHFFCG----------DEGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMT 644
            :....:|:|:.||.||||          .|....|.:...|:...|....:|:..|.|...:.|.
  Fly   612 QFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVMQTLANFEEFSREFGCDKKAKMQ 676

  Fly   645 SADQCPFW 652
            ::.:|..|
  Fly   677 ASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	156/692 (23%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	156/694 (22%)