Protein Alignment Nepl4 and Nep6

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 173/695 - (24%)
• Similarity: 283/695 - (40%)
• Gaps: 154/695 - (22%)

  Fly    44 QQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGSHTTATMISESQINRQY-EDLFLQLLR--NP 105
            ||.:|   :..|:|..|||:|:.||||.|.    |:|:..::....:..:: .:|.|||:|  ..
  Fly    29 QQQLD---NDTDAEVKPCENFHQYACGNWY----SNTSQRILGAHDMRSKWVANLKLQLIRYLEE 86

  Fly   106 SAPEYGYPMFAKV------LAHYQSCIALEKPDLRRYIELLDRD-----LLASL--NSTHWMHLL 157
            |:....:.....|      |.....|..|....:|.|.:.|.|.     |||:.  .|..|:...
  Fly    87 SSSTDSFSANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANHTGGSFDWVLAN 151

  Fly   158 AALGRYGYHGHY-VQVEVRWYNATHHMIFLLPHNRHLNLSLTQDIYDALSQDGSSWPPLHQ---- 217
            |||..||..|.: :.|:..|.:|...:.::||..           :|.|.:|......|:|
  Fly   152 AALRTYGAQGLWRLLVKDNWQSADQRIFYMLPPK-----------FDLLGRDDELNEFLYQRYLK 205

  Fly   218 ---------------LQEQFRSLEQNLVRLAKPHSADDTF---RNYSLDQIRTEVP--------- 255
                           |.|:..:.|::|.:|. |:.|:.|.   :..||..:.:::|
  Fly   206 ILLLELGLRVRRAALLAEKLVAFEKSLQKLL-PNDAEQTLVLRKPQSLKDLESQLPRLELKRYFE 269

  Fly   256 ----GLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEYL--NTVDTLLLNRYSLARFLSHLLE 314
                |:.||.  :|.|          .|.|||.::||...|  :|.|.::|:.:.       ||:
  Fly   270 TILEGIDWDS--KTLL----------LVADLDYLQGLQRLLAEHTSDPMVLSTWL-------LLQ 315

  Fly   315 LP-HNPLATWESGQRSRGRN-CIRHMRRSV-----YLPMNYVYERSFYSRRRHADELVIHSV--- 369
            || :..|...:..:....|| |:..:|:.:     .|.|..|...|:    :...:..|..:
  Fly   316 LPAYFELRLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESY----QDVYDTAIQQIAVL 376

  Fly   370 FQQLQSQLELRV-QHNAFNLSQDLVKSLQA--KVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRD 431
            |:.|:.|.||.: :...||  :|||....|  |:..||:    |.|.:.:..      ....|..
  Fly   377 FRDLKQQFELVLNETEVFN--EDLVTRNLARDKLRAMRL----LTPRLQDPI------NGGPGTP 429

  Fly   432 FYENHLNSLLYYYTLVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPYSYV 496
            ....:.::.|...:|     |.:..|.|.::.......|..|.:::|  |:....|.|.:|...:
  Fly   430 QLGGNCDANLLQLSL-----SQAKLEYRQVFGEPVTSVPADPLSVNA--YYRLKLNRIELPLGLM 487

  Fly   497 KRPFF--------DANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQGNLRNFSDQLGEVELYN 553
            ..|..        |..   |.|...|...|.||::||||.|.::|||.|.|.|.......:..:.
  Fly   488 ATPLIQQQCSKEADTR---AKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFG 549

  Fly   554 GAVGC-----LNSSAVMLNERTSDVSGSRLAMQTYGGDWLTRSG--NGRLYFLQFAHFFCG---- 607
            ...||     .:::.:.:||..:|..|.|||:.||    ..|||  |.|.:|:.||..:||
  Fly   550 LRAGCYLGVRYSNATLTVNENIADTEGLRLALDTY----RHRSGATNLRTFFVAFAQNWCGTVAS 610

  Fly   608 DEGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQCPFW 652
            ..|...|...::|:|..:|.:|:|.:.|.|...|.|...::|..|
  Fly   611 TSGLSQHAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	167/677 (25%)
		GluZincin	59..649	CDD:301352	166/675 (25%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	169/684 (25%)
		M13	40..653	CDD:189000	166/677 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920