Protein Alignment Nepl4 and frma

DIOPT Version :10

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 146/637 - (22%)
• Similarity: 256/637 - (40%)
• Gaps: 117/637 - (18%)

  Fly    57 EKNPCEDFYAYACGKWRAKHGSHTTATMISESQINRQYEDLFLQLLRNPSAPEYGYPMFAKVLAH 121
            :.:||::||..|||.|.|.|.:.:..:.:.....|  |::....||.|..  |...|.|.:.|.:
  Fly    24 QADPCQNFYKVACGNWSASHATDSYESFMDRLDYN--YQEKLADLLDNER--EDDEPHFLQQLRN 84

  Fly   122 -YQSC-IALEKPDLRRYIELL-------DRDLLASLNSTHWMHLLAALGRYGYHGHYVQVEVRWY 177
             |.:| ..|.:..:.|.:|.|       :.:|...|.:...:.:|..|.....:..:.|
  Fly    85 FYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQ------ 143

  Fly   178 NATHHMIFLLPHNRHLNLS------LTQDIYDALSQDGSSWPPLHQLQEQFR--------SLEQN 228
                    |:.|.:|.:.:      ||::::|.|      |..|.::...|:        .||:.
  Fly   144 --------LMSHRKHWDPNTTNREPLTREMFDKL------WASLPKIPFPFKEYYWRELSELEEK 194

  Fly   229 LVRLAKPHSADDTFRNYSLDQIRTEVPG---LHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVE 290
            ::...   |.||.|.:   ..:.|.:|.   :.|..           ||..:        |.|.:
  Fly   195 IMSYG---SEDDGFDS---GDLVTRIPPFWMMPWPN-----------GNITY--------ENLSQ 234

  Fly   291 YLNTVDTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVYLPMNYVYERSFY 355
            ..:.:| :..|.:.|. ::...|:|....::| ||....|.: |....|:.:..|..::.|:
  Fly   235 MAHWLD-IKANEFILT-YIYMRLKLVAEGVST-ESWHIDRDQ-CAEQSRQILSHPAAWLVEK--- 292

  Fly   356 SRRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPPNVTEQFYW 420
            :..|..:|.|:..:|.:|:.:...::..|..|.::.....|..|:.:||:.:..||.|.:.|
  Fly   293 NHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQ--- 354

  Fly   421 DSDRRWSVGRDFYENHLNSLLYYYTLVADL-ESSSDQEERDIWY---------SFNMHTPEFPDN 475
            ...||  :.|.:.:.|:|:..|:..|...| .|.|.::...:|.         |....:..:|..
  Fly   355 SMVRR--IERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQ 417

  Fly   476 ID-----ATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDA 535
            :.     |:.::....|::.||.|.::.||:.......|.|..|...||||:.|.||::.:.:.:
  Fly   418 VRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSS 482

  Fly   536 QGNLRNFSD-QLGEVELYNGAVGCLNSS-AVMLNERTSDVSGSRLAMQTYGGDWLTRSGNGR--- 595
            .|...:..| :|.....:...:|||... .....|:.:|.||..||...|.....|.....|
  Fly   483 HGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAE 547

  Fly   596 -------LYFLQFAHFFCGD-EGDQYHDSGS--QRLNYALGQVPQFAEVFRC 637
                   .:|..||.|||.| |..|.||.||  :|:|.|:.....|.|.|.|
  Fly   548 ELVTQKQQFFHNFAQFFCSDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	146/635 (23%)
frma	NP_572226.2	GluZincin	25..601	CDD:472708	146/636 (23%)