Protein Alignment Nepl4 and Kel

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 147/712 - (20%)
• Similarity: 275/712 - (38%)
• Gaps: 153/712 - (21%)

  Fly    38 CNSTINQQHIDTLMSYVDSEKNPCEDFYAYACGKWRAKHGSHTTATMISESQINRQYEDLFLQLL 102
            |.|.:..:.::..::..:....||.||:::||.|   .:|:..:...::|...:|.:     :||
  Rat    58 CESPVCMELVNHYLASGNRSAAPCTDFFSFACEK---ANGTSNSFQALAEENKSRLW-----KLL 114

  Fly   103 RNPSA--PEYGYPMFAKVLAHYQSCI---ALEKPDLRRYIELLDRDLLASLN-STHW------MH 155
            ..|.:  .|.|.   .|....|.||:   |:|.......::::..  |...| |.:|      .:
  Rat   115 EAPGSWHLESGE---EKAFQFYNSCMDTDAIEASGTGPLVQIIKE--LGGWNISGNWTFFDFNQN 174

  Fly   156 LLAALGRYGYHGHYVQVEVRWYNATHHMIFLLPHNRHLNLSLTQD----IYDAL----------- 205
            |...:.:|| |..:.:..:..:.|..|...:.......::.|.||    :|..:
  Rat   175 LRLLMSQYG-HFPFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQILREYVTYLNRL 238

  Fly   206 ----------SQDGSSWPPLHQLQEQFRSLEQNLVRLAKP----HSADDTFRNYSLDQIRTEVPG 256
                      :|..:||..:      |.|   .|.:..:|    .:.|..|...::|.::...|.
  Rat   239 GTLLGSNPQEAQQHASWSIV------FTS---RLFQFLRPQQQQQAQDKLFHVVTIDALQEMAPA 294

  Fly   257 LHW---DEALRTQLGRSVPGNHVFQVDDLDAI--------EGLVEY---------LNTVDTL--- 298
            :.|   .:|:.|.:  |:..:...||.|||.:        |||:.:         |..||||
  Rat   295 IDWLSCLQAIFTPM--SLSPSQTLQVHDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLSPA 357

  Fly   299 LLNRYSLAR-----FLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVYLP---MNYVYERSFY 355
            |..::..||     .|..|.|.|  ||..:     .|...|: ....|.:.|   ..:|:|....
  Rat   358 LATKFQEARRELTQKLRKLKERP--PLPAY-----PRWMKCV-EQTGSFFEPTLAALFVHEAFGP 414

  Fly   356 SRRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVG----NLPPNVTE 416
            |.|..|.||     |.:::..:.:|::..:: :|::..|....|:.|:::.:|    .|...:.:
  Rat   415 SIRSAAMEL-----FAEIKDAVIVRLKKLSW-ISEETRKEALNKLTQLQVEMGAPKRALKTEMAK 473

  Fly   417 QFYWDSDRRWSVGRDFYENHLNSLLYYYTLVADLESSSDQEERDIWYSFNMHT-PEFPDNIDATP 480
            |.|.|.    .:|..|.::.|:.          :.|...::.|.....|..|. .:.|.::.|
  Rat   474 QEYSDI----QLGPSFLQSFLSC----------VRSLQGRKVRSFLQPFPYHRWQKSPWSVSA-- 522

  Fly   481 YFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQG-NLRNFSD 544
            |:....:::..|...::.|||...:..|:.:|.:.:.:.|:::|.|...|:...... :.|...:
  Rat   523 YYSVPDHVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHIFFQFLLPGGCPACDTRALQE 587

  Fly   545 QLGEVELYNGA-----VGCLNSSAVMLNERTSDVSGSRLAMQTYGGDWLTRSGN----------G 594
            .|..:|....|     :...|.|..:| |..:|:.|..:|.|.|......|:|.          .
  Rat   588 ALLCLEHRYAAFPLPSMSSFNGSHTLL-ENAADIGGVAIAFQAYRKRITERTGELTLPNQELSPY 651

  Fly   595 RLYFLQFAHFFC----GDEGDQYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQCPFW 652
            :|:|..:|...|    ..:....|.....|::..|...|.||:.|.|..||.:..:.:|..|
  Rat   652 QLFFRSYAQVMCRELISQDPQDTHSPPRLRVHGPLSNSPDFAKHFLCPSGSLLNPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	143/688 (21%)
		GluZincin	59..649	CDD:301352	143/686 (21%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	144/693 (21%)
		M13	78..711	CDD:189000	143/688 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880