Protein Alignment Nepl4 and nep-20

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 135/706 - (19%)
• Similarity: 248/706 - (35%)
• Gaps: 201/706 - (28%)

  Fly    50 LMSYVDSEKNPCEDFYAYACGKWR-----AKHGSHTTATMISESQINRQYEDLFLQLLRNPSAPE 109
            |.:|.|:..:.|.:||...|||::     .||.......::  .:|.|::      |.||.|:..
 Worm   227 LSAYQDTSVSKCHNFYKATCGKYKHHQALDKHRDAKKKEVV--KRIVREF------LRRNESSIT 283

  Fly   110 YGYP-----MFAKVLAHYQSCIALEKPDLRRYIELLDR---------DLLASLNSTHWMHLLAAL 160
            ..:.     ||.|.....|:...|   |:.:.||.:..         |::.:||.  ::..|..|
 Worm   284 SKFEPAIRLMFGKCNKFSQNKTYL---DIFKDIEKIGPWPVLKSDWVDVMFNLND--YLLSLVEL 343

  Fly   161 G--RYGYHGHYVQVEVRWYNATHHMIFLLPHNRHLNLSLTQDIYDALSQDG--SSWPPLHQLQEQ 221
            |  .:|    ..::|.|.. |......:.|..:.....|.:.|.:.|..:|  :....|.:...:
 Worm   344 GFTDFG----LFKLEFRQL-AFGQFPVIAPSEQKQGNQLEKIILEILEANGVQADRQKLSKYLRE 403

  Fly   222 FRSLEQNLVRLAKPHSADDTFRNYSLDQIRTEVPGLHWDEA---------LRTQLGRSVPGNHVF 277
            :...:..|..::...::....| |:...:...:..|....|         .|.|.|..:..:..|
 Worm   404 YSEFKSQLRHMSLEGTSVKYIR-YNASTLSVNISALVQKMAPMSTSSGLVRRIQSGILITNSSSF 467

  Fly   278 QVDDLDAI------EGLVEYL--NTVDTLLLNRYSLARFLSHLL--ELPHNPLATWESGQRSRGR 332
            ...:||||      ..|..||  :.:|.:..:..|.|:...|.|  .||...|..
 Worm   468 FGKNLDAIIQQTHKRTLANYLIFHFIDAVTFDLTSGAKHSEHTLIDLLPRGSLQV---------- 522

  Fly   333 NCIRHMRRSVYLPMNYVYERS-------FYSRRRHADELVI--------HSVFQQLQSQLELRVQ 382
                       |..::|.|..       ....::|..|::.        |.||::.:.:..:|
 Worm   523 -----------LSQDFVDEEDQGVMVEMAKDLKKHVVEMISEGSSLDKGHLVFEEKERRKLIR-- 574

  Fly   383 HNAFNLSQDLVKSLQAKVHQMRINVGNLPPNVTEQFYWDSDRRWSVGRDFYENHLNSLLYYY--- 444
                 ..||::...:..:..:..|...|  |:|                 |.:.|:.::...
 Worm   575 -----KVQDILVVTKYPLEILNQNFEKL--NLT-----------------YSDSLHKIIQKLRRF 615

  Fly   445 ---TLVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFW 506
               .|:..|....|..::.:|.|  .|..:..:::           ||..|  .:..|:||.:
 Worm   616 RSEQLIEYLGGDLDPTDKGMWGS--AHYEQATNDL-----------IIIAP--IIDGPYFDTS-- 663

  Fly   507 PALLYGDLAN------TLGHEIMHAFDTDLVDYDAQGNLRNF--SDQLGEVELYNGAVGCLNSSA 563
                |.:..|      .:..|:..:.|:..:..|.:|:..|:  |:.|   :.::..|.|.....
 Worm   664 ----YPNYVNIFFMGFIISRELGRSLDSVRIRKDEKGHTENWLKSESL---KRFDNNVKCWRKKI 721

  Fly   564 V---MLNERTSDVSG---SRLAMQTYGGDWLTRSGNG---------------RLYFLQFAHFFC- 606
            .   .|||..:|..|   |.:|::.:     .:..||               :::|...|.:||
 Worm   722 TGTRFLNEMLADHVGHEASFMALKKW-----EKEMNGTIVEKIRGYESMTMEQIFFHLQALYFCR 781

  Fly   607 ---GDEGD-------QYHDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQCPFW 652
               |..|:       |::   |.|:|.|...:||||:.|.|.....|.|..:|.|:
 Worm   782 PPGGSTGELTAKDARQHY---STRVNEAFKNMPQFAKAFGCSSNQNMNSKTKCTFF 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	130/694 (19%)
		GluZincin	59..649	CDD:301352	130/692 (19%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920