Protein Alignment Nepl4 and nep-9

DIOPT Version :9

• Sequence 1: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 737
• Identity: 150/737 - (20%)
• Similarity: 242/737 - (32%)
• Gaps: 252/737 - (34%)

  Fly    50 LMSYVDSEKNPCEDFYAYACGKWRAKHG-----------------------SHTTATMISESQI- 90
            |.:|.|:....|||||...|..::....                       ..:|.|..|||.|
 Worm    76 LKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKLVRGFLQRDESTFTSESESAIK 140

  Fly    91 -----------NRQYEDLFLQLLRNPSAPEYGYPMFAKVLAH--YQSCIALEKPDLRRYIELLDR 142
                       |..|.|:|..:.:..|.|         ||.|  ..|...|:
 Worm   141 LIFGKCDELSRNTSYLDIFKDIKKIGSWP---------VLEHNWKDSMFNLD------------- 183

  Fly   143 DLLASLNSTHWMHLLAALGRYGYHGHYVQVEVRWYNATHHMIFLLPHNRHLNLSLTQDIYDALSQ 207
            |::|.         |..||...: |.: ::|:|.....|..:|:..........|.:.|...|..
 Worm   184 DVIAK---------LVKLGSTDF-GLF-KLELRKLAFGHFAVFVSSKQEQNIHQLEKTILGILKA 237

  Fly   208 DGSSWPPLHQLQEQFRSLEQNLVRLA------KPHSADDTFRNYSL--DQIRTEVPGLHWDEALR 264
            :|        :|:..:.|..:|...:      |....::|:..|.|  ..| .|..|:   .:|.
 Worm   238 NG--------IQQDRKELSDDLKDYSDFKNHLKEFYQEETYIEYRLYAGSI-VENLGI---SSLT 290

  Fly   265 TQLGRSVPG----NHVFQVDDLDAIEGLVEYLNTVDTLLLN-------------------RYSLA 306
            ||:.....|    |||.|                 .||:.|                   :.:||
 Worm   291 TQMALKSTGLDVFNHVNQ-----------------RTLITNSSLFFGEENNLGMIIQKTPKRTLA 338

  Fly   307 RFL-SHLLELPHNPLATWESGQRSRGRNCIRHM-----RRSV-YLPMNYVYERSFYSRRRHADEL 364
            .|| .|.:::....||       :..:.|...:     |.|: .|..|:|.|.:       .|::
 Worm   339 NFLIFHFIDVMTTDLA-------NATKACKETLIDLLPRASIQVLSRNFVNEDA-------QDDM 389

  Fly   365 VIHSVFQQLQSQLELRVQHNAFNLSQDLV------KSLQAKVHQMRINVGNLPPNVTEQFYWDSD 423
            |  .:.|.|::::...:.::.|.....||      |.|..||..:.| |...|..|.:
 Worm   390 V--KMAQDLKTKITEMIDNSPFFTKFHLVFDAEEQKKLIQKVKAIGI-VTEYPQEVLD------- 444

  Fly   424 RRWSVGRDFYENHLN-SLLYYYT-----------LVADLESSSDQEERDIWYSFNMHTPEFPDNI 476
                  |||...:|. |...|.|           |:..|....|..:..:|.|  .|..:..:|:
 Worm   445 ------RDFERLNLTPSDSIYRTIQKLRRLRSEQLIEHLGGDLDPTDTRVWGS--AHYDQTTNNL 501

  Fly   477 DATPYFYCLGNIIFVPYSYVKRPFFDA---NFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQG- 537
                       .||.|  .:..|:||.   |:....|.|.:   ||.|:..:.|:..:..|.:|
 Worm   502 -----------TIFAP--IIDGPYFDTSYPNYVNQFLMGFI---LGRELGRSLDSVRIRKDEKGQ 550

  Fly   538 --------NLRNFSDQLG-EVELYNGAVGCLNSSA---------VMLNERTSDVSGSRLA----- 579
                    :|:.|.:.|. ..|.|:.:...|.|.:         .:.||..:|..|...:
 Worm   551 TENWLKPESLKRFDEHLKCWAEKYDKSADPLKSESKGIRQIEGRYIQNEMFADFIGHEASWRAFM 615

  Fly   580 ---------MQTYGGDWLTRSGNGRLYFLQFAHFFCGDEG--------DQYHDSGSQRLNYALGQ 627
                     ::|:....|.     |::|...|.:||....        .::|...|.|:|.|...
 Worm   616 KLDVKNEEVLETFKVIKLR-----RMFFNVQALYFCRPPSGSTDWLSYQEHHQHYSFRVNGAFKN 675

  Fly   628 VPQFAEVFRCHVGSGMTSADQC 649
            :||||..|.|.....|...::|
 Worm   676 MPQFALAFECASDDDMNPQNKC 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	147/728 (20%)
		GluZincin	59..649	CDD:301352	146/726 (20%)
nep-9	NP_494531.2	M13	87..698	CDD:189000	147/726 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910