DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and ANGPTL1

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001363692.1	Gene:	ANGPTL1 / 9068	HGNCID:	489	Length:	491	Species:	Homo sapiens

Alignment Length:	199	Identity:	75/199 - (37%)
Similarity:	122/199 - (61%)	Gaps:	2/199 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GIYTVQVLGLK-PFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKL 152
            |||.::..... |.|:.|:..:...||||:.:||...:||||:|..||.|||.:||::::||:.:
Human   292 GIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENI 356

  Fly   153 HAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFST 217
            :.::....::|.|.|||:..:..||.|....:|.|::||.: :||.:.|:|||||:.:..:.|:|
Human   357 YMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRL-RLGTYQGNAGDSMMWHNGKQFTT 420

  Fly   218 FDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQM 282
            .|||.|.:..|||..:.|.||:..|.:|||.|::.:|...:.....||.|..:|..|||.:.:||
Human   421 LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQM 485

  Fly   283 MVRP 286
            |::|
Human   486 MIKP 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	75/199 (38%)
ANGPTL1	NP_001363692.1	PB1	74..138	CDD:383100
ANGPTL1	NP_001363692.1	FReD	275..490	CDD:238040	75/199 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3350
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40314
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.810