DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and FIBCD1

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001138578.1	Gene:	FIBCD1 / 84929	HGNCID:	25922	Length:	461	Species:	Homo sapiens

Alignment Length:	297	Identity:	98/297 - (32%)
Similarity:	140/297 - (47%)	Gaps:	63/297 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LKSLYKLVLALLEENQSNA-----STENI------------QKSSSDLNTTGLSGRYPSQC---- 81
            |:|....::.||.|:|.:.     |..:|            .::.:||......|..|..|
Human   175 LQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGS 239

  Fly    82 ----------------------PTYPPAHGIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNK 124
                                  ||:.||            .|||.||....|.||||..||....
Human   240 RPRDCLDVLLSGQQDDGVYSVFPTHYPA------------GFQVYCDMRTDGGGWTVFQRREDGS 292

  Fly   125 LNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDE----IF-I 184
            :||||.|..|::|||:|.|:.::||.::||:|....:||::.|||||..|.||.|..    :| :
Human   293 VNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSV 357

  Fly   185 ESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFG 249
            :.|...|.:| :.:::|.||||::.:....|:|.|||:|....|||..|.||||:.||..|||.|
Human   358 DPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNG 421

  Fly   250 IYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286
            .|::|....|..  |:.|.||....||.|..:|.:||
Human   422 QYLRGAHASYAD--GVEWSSWTGWQYSLKFSEMKIRP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	87/242 (36%)
FIBCD1	NP_001138578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..238		5/23 (22%)
		FReD	241..457	CDD:238040	85/231 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3350
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122246
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3915
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm40314
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.860