DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and angptl2b

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001119950.1	Gene:	angptl2b / 503514	ZFINID:	ZDB-GENE-050624-1	Length:	519	Species:	Danio rerio

Alignment Length:	256	Identity:	83/256 - (32%)
Similarity:	132/256 - (51%)	Gaps:	40/256 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 NKPELKSLYKLVLALLEENQSNASTENIQKSSSDLNTTGLSGRYPSQCPTYPPAHGIYTVQVLGL 98
            |||  ...:|..|..||:..:|:....::..:::
Zfish   295 NKP--SGPWKDCLEALEDGHTNSGMHLVKPDNTN------------------------------- 326

  Fly    99 KPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHEL 163
            |..||.||......||||:.||....:||||:|..||.|||.:||::::||:.::.||....::|
Zfish   327 KLMQVWCDQRQDPGGWTVIQRRMDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWITNQGNYKL 391

  Fly   164 YIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKN 228
            .:.|||:.|:..:|.|....:|.|..||.: ::|.:.|:||||:..:..:.|:|.|||:|.:..|
Zfish   392 LVTLEDWSGRKTFAEYASFRLEPEADFYRL-RVGRYHGNAGDSLTWHNGKQFTTLDRDHDVYTGN 455

  Fly   229 CAEEYVGAWWHLNCTYSNLFGIYVKGDEGQY---FQWKGIVWHSWRTESYSYKVMQMMVRP 286
            ||....|.||:..|.:|||.|::.:|  |.|   :| .|:.|..:|..:||.|.:.||:||
Zfish   456 CAHYQKGGWWYNACAHSNLNGVWYRG--GHYRSRYQ-DGVYWAEFRGGAYSLKKVVMMIRP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	75/214 (35%)
angptl2b	NP_001119950.1	RILP-like	98..216	CDD:304877
angptl2b	NP_001119950.1	FReD	299..513	CDD:238040	78/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6515
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810