DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and angptl1b

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001186899.1	Gene:	angptl1b / 334311	ZFINID:	ZDB-GENE-030131-6243	Length:	471	Species:	Danio rerio

Alignment Length:	274	Identity:	85/274 - (31%)
Similarity:	141/274 - (51%)	Gaps:	24/274 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RNKPEL-----KSLYKLVLALLEENQSNASTENIQKSSSDL--------NTTGLSGRYPSQCPTY 84
            |:.|.|     :::...|..:..|.|||:.||..:..::..        |.:.|.|.:.......
Zfish   200 RDPPSLPQVLPENIPVFVPRVSNEIQSNSWTEEQRPGAAAADTGERPAQNNSSLKGPFRDCYAAL 264

  Fly    85 PPAHGIYTVQVL----GLKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDF 145
            ...|.:....:|    .|.|.|..|:.::...|||::.||....:||.|.|..||.|||.:||:.
Zfish   265 QAGHSVSGAILLQPDDTLTPVQAWCEHDVDRGGWTLIQRRKDGAVNFSRDWDSYKLGFGDVDGEH 329

  Fly   146 FIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHN 210
            ::|||.::::.:.:.::|.:.:||:..:..||.|....:|.|::.|.: :||.:.|:||||:..:
Zfish   330 WLGLDTIYSLGRQEEYKLLVEMEDWMEKKVYAAYSSFHLEPESQSYRL-RLGLYQGNAGDSLTSH 393

  Fly   211 RNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQY---FQWKGIVWHSWRT 272
            ..:.|:|.|||:|.:..|||....|.||:..|..:||.|::..|  |.|   || .||.|..:..
Zfish   394 NGRQFTTLDRDHDAFSGNCAHFQKGGWWYNACGQTNLNGVWYSG--GVYRSRFQ-DGIFWADYGG 455

  Fly   273 ESYSYKVMQMMVRP 286
            ..||.|.::||:||
Zfish   456 GFYSMKSVRMMIRP 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	72/218 (33%)
angptl1b	NP_001186899.1	IncA	<58..171	CDD:282066
angptl1b	NP_001186899.1	FReD	255..470	CDD:238040	73/219 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910