DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and Angptl6

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001100172.1	Gene:	Angptl6 / 298698	RGDID:	1311141	Length:	457	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	90/255 - (35%)
Similarity:	136/255 - (53%)	Gaps:	29/255 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LEENQSNASTENIQKSSSDLNTTGLSGRYPSQCPTYP------------PAH---GIYTVQVLGL 98
            :.|:|...|.......||.|.|..::      .||.|            ..|   |:|.:: ||.
  Rat   210 IPEHQREQSLRQQGPPSSPLPTGHVA------VPTRPVGPWRDCAEAQGAGHWQSGVYELR-LGR 267

  Fly    99 KPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHEL 163
            :...|.|:.:..|.||||:.||....:|||.:|..||.|||:.||::::||:.:|.:|....|||
  Rat   268 RVVPVWCEQQQEGGGWTVIQRRQDGSVNFFTNWQHYKVGFGRPDGEYWLGLEPVHQVTSRGDHEL 332

  Fly   164 YIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKN 228
            .|.|:|:.|:...||||...:|.|:..|.: :||::.||||||:..:.::.|:|.|||.|.:..|
  Rat   333 LILLKDWGGRGARAHYDSFSLEPESDHYRL-RLGQYHGDAGDSLSWHSDKPFNTVDRDRDSYSGN 396

  Fly   229 CAEEYVGAWWHLNCTYSNLFGIYVKGDEGQY---FQWKGIVWHSWRTESYSYKVMQMMVR 285
            ||..:.|.||:..|.:|||.|::..|  |.|   :| .|:.|..:|..:||.|...|:.|
  Rat   397 CALYHRGGWWYHACAHSNLNGVWYHG--GHYRSRYQ-DGVYWAEFRGGAYSLKKAAMLTR 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	83/228 (36%)
Angptl6	NP_001100172.1	Uso1_p115_C	66..>157	CDD:282695
Angptl6	NP_001100172.1	FReD	242..453	CDD:238040	79/215 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810