Protein Alignment CG9500 and ANGPTL3

DIOPT Version :10

• Sequence 1: NP_609018.3
• Gene: CG9500 / 33888
• FlyBaseID: FBgn0031804
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_055310.1
• Gene: ANGPTL3 / 27329
• HGNCID: 491
• Length: 460
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 87/308 - (28%)
• Similarity: 137/308 - (44%)
• Gaps: 52/308 - (16%)

  Fly    27 QNDTAIRNKPELKSL----------YKLVLALLEE--NQSNASTENIQKSSSDLNTT-------- 71
            ||.......||:.||          .|.:|..:|:  .|.|.....|::..:.|..|
Human   150 QNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEI 214

  Fly    72 GLSGR----------------------YPSQCPTY----PPAHGIYTVQVLGLKPFQVSCDAEIA 110
            .||.:                      .|::|.|.    ....|:|.::....:.|.|.||. |:
Human   215 SLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDV-IS 278

  Fly   111 GTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTR 175
            |:.||::..|.....||..:|..||.|||:|||:|::||:|:::|.|...:.|.|.|||::....
Human   279 GSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKH 343

  Fly   176 YAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGA-WWH 239
            |..| ..::.:....|.: .|...||:..:::..|::..|||:|....| |.||.|.|.|. |||
Human   344 YIEY-SFYLGNHETNYTL-HLVAITGNVPNAIPENKDLVFSTWDHKAKG-HFNCPEGYSGGWWWH 405

  Fly   240 LNCTYSNLFGIYVK-GDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286
            ..|..:||.|.|.| ..:.:..:.:|:.|.|.....||.|..:|::.|
Human   406 DECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHP 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	71/239 (30%)
ANGPTL3	NP_055310.1	GumC	<81..>205	CDD:442439	13/54 (24%)
		FReD	243..453	CDD:238040	70/213 (33%)