DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9500 and Tnr

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_037177.2	Gene:	Tnr / 25567	RGDID:	3886	Length:	1358	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	102/298 - (34%)
Similarity:	155/298 - (52%)	Gaps:	46/298 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LSFYSTEA------MDSESFQNDTAIRNKPELKSL-----YKLVLALLEENQSNASTENIQKSSS 66
            |::.||:.      :|:|    ||.||    |:.|     |.::|...:|...::.|       |
  Rat  1073 LTYKSTDGSRKELIVDAE----DTWIR----LEGLSENTDYTVLLQAAQEATRSSLT-------S 1122

  Fly    67 DLNTTGLSGR---YPSQCPTY----PPAHGIYTVQVLG--LKPFQVSCDAEIAGTGWTVMARRTS 122
            .:.|||  ||   :|..|..:    ....|:||:.:.|  ....||.||....|.||.|..||.:
  Rat  1123 TIFTTG--GRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQN 1185

  Fly   123 NKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTR-YAHYDEIFIES 186
            .:.:|||.||:|:.|||.|:.:|::|||.:|.||....:||.:.:.|  ||.. :|:||:..:|.
  Rat  1186 GQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYELRVDMRD--GQEAVFAYYDKFAVED 1248

  Fly   187 ENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIY 251
            ....|.: ::|.:.|.||||:.:::.:.|||.|||||....|||..|.||||:.||..:||.|.|
  Rat  1249 SRSLYKL-RIGGYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKY 1312

  Fly   252 VKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCH 289
                 |:....:||.|:.|:...:|...::|.:||..|
  Rat  1313 -----GESRHSQGINWYHWKGHEFSIPFVEMKMRPYIH 1345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	80/220 (36%)
Tnr	NP_037177.2	exchanger_TraA	<190..>328	CDD:411343
		EGF_Tenascin	203..231	CDD:376143
		fn3	328..398	CDD:394996
		fn3	416..496	CDD:394996
		fn3	507..586	CDD:394996
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:394996
		fn3	776..855	CDD:394996
		fn3	865..944	CDD:394996
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020	16/68 (24%)
		FReD	1134..1342	CDD:238040	78/215 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810