DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and Tnc

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_001356140.1	Gene:	Tnc / 21923	MGIID:	101922	Length:	2110	Species:	Mus musculus

Alignment Length:	309	Identity:	95/309 - (30%)
Similarity:	142/309 - (45%)	Gaps:	50/309 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FYSTEAMDSESFQNDTAIRN-KPELKSL--YKLV-------------------LALLEENQSNAS 57
            |.:||.      |::||:.. :|...|:  |.||                   .:|.:.:.|...
Mouse  1802 FTATEV------QSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHY 1860

  Fly    58 TENIQKSSSDL---------NTTGLSGRYPSQCP----TYPPAHGIYTVQVLGLK--PFQVSCDA 107
            :..||..|..|         .|.||...:|..|.    ......|:||:.:.|.|  ..:|.||.
Mouse  1861 SARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDM 1925

  Fly   108 EIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEG 172
            ...|.||.|..||.:.:.:|:|:|..|..|||....:|::|||.|..||....:||.:.|:| .|
Mouse  1926 TSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQD-HG 1989

  Fly   173 QTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAW 237
            ::.||.||...:......|.: |:..::|.|||||.::..::|||:|:|.|....|||..|.||:
Mouse  1990 ESAYAVYDRFSVGDAKSRYKL-KVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAF 2053

  Fly   238 WHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286
            |:.||...||.|.|...:..|     |:.|..|:...||.:..:|.:||
Mouse  2054 WYKNCHRVNLMGRYGDNNHSQ-----GVNWFHWKGHEYSIQFAEMKLRP 2097

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	75/217 (35%)
Tnc	NP_001356140.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	69..91
		EGF_2	222..247	CDD:285248
		EGF_2	345..372	CDD:285248
		EGF_2	377..403	CDD:285248
		EGF_2	408..434	CDD:285248
		EGF_2	468..496	CDD:285248
		EGF_2	504..527	CDD:285248
		EGF_2	533..558	CDD:285248
		EGF_2	592..620	CDD:285248
		FN3	624..710	CDD:238020
		fn3	713..793	CDD:333790
		FN3	804..891	CDD:238020
		fn3	894..976	CDD:333790
		fn3	986..1064	CDD:333790
		fn3	1075..1147	CDD:333790
		fn3	1169..1246	CDD:333790
		fn3	1257..1336	CDD:333790
		fn3	1348..1417	CDD:333790
		fn3	1442..1519	CDD:333790
		fn3	1530..1610	CDD:333790
		fn3	1620..1699	CDD:333790
		fn3	1711..1785	CDD:333790
		fn3	1797..1869	CDD:333790	15/72 (21%)
		Fibrinogen_C	1889..2098	CDD:278572	75/216 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710