DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and Fgl2

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_032039.2	Gene:	Fgl2 / 14190	MGIID:	103266	Length:	432	Species:	Mus musculus

Alignment Length:	317	Identity:	102/317 - (32%)
Similarity:	154/317 - (48%)	Gaps:	60/317 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EAMDSESFQNDTAIRN-KPELKSLYKLVLALLEENQSNASTEN-IQKSSSDLN--TTGLSGRYPS 79
            :.::|:..:..:.::| |.:::.|...:..|...|.:|  .|| :....::|.  ...|.|:. |
Mouse   124 QELESQVNKLSSELKNAKDQIQGLQGRLETLHLVNMNN--IENYVDNKVANLTVVVNSLDGKC-S 185

  Fly    80 QCP------TYPPAHGIY----TVQVLGLK--------------PFQVSCDAEIAGTGWTVMARR 120
            :||      :.|..|.||    ...|||.:              .|:|.||.|..|.||||:..|
Mouse   186 KCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQAR 250

  Fly   121 TSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIE 185
            .....||.|.|.:||.|||.|:.:|::|.||:|.:|||:...|.|.||||.|.|.||.||:.::.
Mouse   251 LDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVA 315

  Fly   186 SENKFYAMTKLGEFTGDAGDSMIHNRNQN-----FSTFDRDNDGWHK-NCAEEYVGAWWHLNCTY 244
            :|...|.: .:|.:.|.|||::..:|:.|     |:|.|||||.:.. ||...|...||..:|..
Mouse   316 NEFLKYRL-HIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLS 379

  Fly   245 SNLFGIYVKGDEGQYFQWK------GIVWHSW------RTESY--SYKVMQMMVRPK 287
            :||        .|:|:..|      ||.|.:|      :...|  |:|..:||:|||
Mouse   380 ANL--------NGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	88/254 (35%)
Fgl2	NP_032039.2	Uds1	72..151	CDD:292096	4/26 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..122
		Fibrinogen_C	202..428	CDD:278572	83/234 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810