DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and Fcna

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_032021.1	Gene:	Fcna / 14133	MGIID:	1340905	Length:	334	Species:	Mus musculus

Alignment Length:	224	Identity:	88/224 - (39%)
Similarity:	122/224 - (54%)	Gaps:	16/224 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KSSSDLNTTGLSGRYPSQCPTYPPAHGIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNKLNF 127
            :|..||.|.|:.            ..|.||:.:...:|..|.||.::.|.||||..||....::|
Mouse   124 RSCKDLLTRGIF------------LTGWYTIHLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSIDF 176

  Fly   128 FRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYA 192
            ||.|..||.|||.|..:|::|.|.||.:|.:...||.:.|:||:|:..||.|....:..|.:.|.
Mouse   177 FRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKYK 241

  Fly   193 MTKLGEF-TGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDE 256
            :| ||:| .|.||||:..:.|.:|:|.|:|||....|||..:.||||:.||..|||.|.|:.|..
Mouse   242 LT-LGQFLEGTAGDSLTKHNNMSFTTHDQDNDANSMNCAALFHGAWWYHNCHQSNLNGRYLSGSH 305

  Fly   257 GQYFQWKGIVWHSWRTESYSYKVMQMMVR 285
            ..|..  ||.|.:.:...|||||.:|.:|
Mouse   306 ESYAD--GINWGTGQGHHYSYKVAEMKIR 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	83/211 (39%)
Fcna	NP_032021.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..117
		Collagen	65..106	CDD:189968
		FReD	123..332	CDD:238040	87/222 (39%)
		A domain, contributes to trimerization. /evidence=ECO:0000250	123..162		13/49 (27%)
		B domain, contributes to trimerization. /evidence=ECO:0000250	163..251		36/88 (41%)
		Carbohydrate-binding. /evidence=ECO:0000250\|UniProtKB:O00602	290..292		1/1 (100%)
		P domain. /evidence=ECO:0000250\|UniProtKB:O00602	325..334		4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3330
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3887
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm43211
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.760