DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and Tnc

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	XP_008761976.1	Gene:	Tnc / 116640	RGDID:	621057	Length:	2202	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	94/307 - (30%)
Similarity:	141/307 - (45%)	Gaps:	44/307 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 STEAMDSESFQNDTAIRN-KPELKSL--YKLV-------------------LALLEENQSNASTE 59
            |...:.:...|::||:.. :|...|:  |.||                   .:|.:.:.|...|.
  Rat  1890 SPRELTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTA 1954

  Fly    60 NIQKSSSDL---------NTTGLSGRYPSQCP----TYPPAHGIYTVQVLGLK--PFQVSCDAEI 109
            .||..|..|         .|.||...:|..|.    ......|:||:.:.|.|  ..:|.||...
  Rat  1955 RIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTS 2019

  Fly   110 AGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQT 174
            .|.||.|..||.:.:.:|:|:|..|..|||....:|::|||.|..||....:||.:.|:| .|::
  Rat  2020 DGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQD-HGES 2083

  Fly   175 RYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWH 239
            .||.||...:......|.: |:..::|.|||||.::..::|||:|:|.|....|||..|.||:|:
  Rat  2084 AYAVYDRFSVGDAKSRYKL-KVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWY 2147

  Fly   240 LNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286
            .||...||.|.|...:..|     |:.|..|:...||.:..:|.:||
  Rat  2148 KNCHRVNLMGRYGDNNHSQ-----GVNWFHWKGHEYSIQFAEMKLRP 2189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	75/217 (35%)
Tnc	XP_008761976.1	EGF_2	346..372	CDD:285248
		EGF_2	377..403	CDD:285248
		EGF_2	408..434	CDD:285248
		EGF_2	434..465	CDD:285248
		EGF_2	468..496	CDD:285248
		EGF_2	504..527	CDD:285248
		EGF_2	533..558	CDD:285248
		EGF_2	592..620	CDD:285248
		FN3	624..710	CDD:238020
		fn3	713..793	CDD:278470
		FN3	804..891	CDD:238020
		fn3	894..976	CDD:278470
		fn3	986..1064	CDD:278470
		fn3	1075..1154	CDD:278470
		fn3	1166..1241	CDD:278470
		fn3	1257..1336	CDD:278470
		fn3	1348..1417	CDD:278470
		fn3	1444..1509	CDD:278470
		fn3	1534..1606	CDD:278470
		fn3	1622..1702	CDD:278470
		FN3	1712..1798	CDD:238020
		fn3	1801..1874	CDD:278470
		fn3	1889..1961	CDD:278470	14/70 (20%)
		Fibrinogen_C	1981..2190	CDD:278572	75/216 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810