DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9500 and tnc

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	XP_004916768.1	Gene:	tnc / 100494697	XenbaseID:	XB-GENE-1002816	Length:	1829	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	98/313 - (31%)
Similarity:	149/313 - (47%)	Gaps:	52/313 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TEAMD------SESFQNDTAIRN-KPELKSLYKLVL---------------------ALLEENQS 54
            |.|:|      :...|:::|:.. ||...::...||                     .||:.:.|
Frog  1512 TTALDGPRDLSASEIQSESALLTWKPPRSTITGYVLIYESVDGTVKEVVVGPDTTSYRLLDLSPS 1576

  Fly    55 NASTENIQKSSSDLN---------TTGLSGRYPSQCP----TYPPAHGIYTVQVLG--LKPFQVS 104
            ......:|..:.|..         |.||...||..|.    ......|:||:.|.|  .:|.:|.
Frog  1577 AQYIARVQAINGDRRSKEIQTIFITIGLLYPYPKDCSQALLNGEADSGLYTIYVNGDQSQPMEVY 1641

  Fly   105 CDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLED 169
            ||..:.|.||.|..|||.....|:|:|..|..|||.::.:||:||:.||.:|....:||.:.|.|
Frog  1642 CDMSVDGGGWIVFLRRTDGSEEFYRNWKTYSAGFGNINNEFFMGLENLHKLTSLGQYELRVDLRD 1706

  Fly   170 FEGQTRYAHYDEIFI-ESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEY 233
             ..:|.||.||:..: :::::|  ..|:..::|.|||||.::..::|||||:|||....|||..|
Frog  1707 -NDETAYAVYDKFSVGDAKSRF--RLKVEGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSY 1768

  Fly   234 VGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286
            .||:|:.||...||.|.|  ||....   :|:.|..|:...||.:..:|.:||
Frog  1769 KGAFWYKNCHRVNLMGRY--GDTNHS---QGVNWFHWKGHEYSIQFAEMKIRP 1816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	81/218 (37%)
tnc	XP_004916768.1	EGF_Tenascin	187..214	CDD:376143
		EGF_Tenascin	249..276	CDD:376143
		EGF_Tenascin	280..307	CDD:376143
		DSL	<295..337	CDD:366627
		EGF_Tenascin	342..369	CDD:376143
		EGF_Tenascin	373..399	CDD:376143
		EGF_Tenascin	404..431	CDD:376143
		EGF_Tenascin	435..461	CDD:376143
		EGF_Tenascin	466..492	CDD:376143
		EGF_Tenascin	497..524	CDD:376143
		EGF_Tenascin	528..554	CDD:376143
		EGF_Tenascin	559..586	CDD:376143
		EGF_Tenascin	590..617	CDD:376143
		fn3	620..691	CDD:365830
		fn3	713..789	CDD:365830
		fn3	799..877	CDD:365830
		fn3	887..969	CDD:365830
		fn3	979..1056	CDD:365830
		fn3	1074..1147	CDD:365830
		fn3	1158..1230	CDD:365830
		fn3	1249..1329	CDD:365830
		fn3	1339..1418	CDD:365830
		fn3	1428..1506	CDD:365830
		fn3	1518..1594	CDD:365830	11/75 (15%)
		FReD	1607..1817	CDD:238040	81/218 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	182	1.000	Domainoid score	I3392
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9330
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000