DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9500 and tnxb

DIOPT Version :9

Sequence 1:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	XP_031747219.1	Gene:	tnxb / 100489649	XenbaseID:	XB-GENE-481849	Length:	2840	Species:	Xenopus tropicalis

Alignment Length:	237	Identity:	81/237 - (34%)
Similarity:	130/237 - (54%)	Gaps:	23/237 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SSSDLNTTGLSGR----YPSQCPTYPPAH-------GIYTVQVLGLK--PFQVSCDAEIAGTGWT 115
            ||:.::|:..:||    :|..|   ...|       |::|:.:.|.|  |..|.||.|..|.||.
Frog  2606 SSAPISTSFTTGRIRYPFPRDC---WEKHMNGDLQSGVFTIYLGGSKDDPLLVYCDMETDGGGWI 2667

  Fly   116 VMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYD 180
            |..||...:.:|:|:|.:||.|||.|..:|::|...||.::...|:||.:.|. ...:..||.|:
Frog  2668 VFQRRIDGRTDFWRNWRQYKEGFGNLTSEFWLGNIALHRLSSLAPYELRVDLR-AGAEAAYAVYE 2731

  Fly   181 EIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYS 245
            :..:|.|:|.:.: ::|.:.|:||||:.::.|..|||.|||.:.....|:..|.||||:.||.|:
Frog  2732 DFRVEGEDKHFRL-RIGAYRGNAGDSLSYHNNMIFSTRDRDAEKRILPCSISYRGAWWYKNCHYA 2795

  Fly   246 NLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPK 287
            ||.|:|....:.|     |:.||:|:...:|....:|.:||:
Frog  2796 NLNGMYGNNKDHQ-----GVNWHTWKGFEFSIPFTEMKMRPQ 2832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9500	NP_609018.3	FReD	76..287	CDD:238040	76/223 (34%)
tnxb	XP_031747219.1	EGF_Tenascin	179..206	CDD:376143
		exchanger_TraA	<400..779	CDD:411343
		EGF_Tenascin	799..826	CDD:376143
		fn3	834..913	CDD:394996
		FN3	923..998	CDD:214495
		fn3	1790..1852	CDD:394996
		fn3	1881..1960	CDD:394996
		fn3	1972..2051	CDD:394996
		fn3	2064..2141	CDD:394996
		fn3	2170..2245	CDD:394996
		fn3	2267..2338	CDD:394996
		FN3	2356..2433	CDD:238020
		fn3	2445..2522	CDD:394996
		fn3	2531..2609	CDD:394996	2/2 (100%)
		FReD	2622..2831	CDD:238040	74/218 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	182	1.000	Domainoid score	I3392
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm14088
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910