DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk14 and ppk19

DIOPT Version :9

Sequence 1:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	124/482 - (25%)
Similarity:	205/482 - (42%)	Gaps:	47/482 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LIDSYISRSHIHGLYLLFLPSMRRRMRVLWALALICACTVLFHVSYLLGDRYHNKQFQTIVAHAH 105
            |.:|: :.|:|||:..:| .......|.||...::.|....|.:..:|..|:..:...:::....
  Fly    33 LCNSF-AHSNIHGMQHVF-GEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLLVSLIETTQ 95

  Fly   106 ASIHHIAFPVVIICNKNRLNWSRLPEIKSLYNITPSQD-----ELFDRILTAYDGFSFHKFNAFD 165
            ..::||.||.|.:|..|..||.|.|  .:.....|...     |.|.::|.:.|..:|..||...
  Fly    96 LPVYHIDFPAVAVCPWNHFNWQRAP--SAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIR 158

  Fly   166 SLLGESLDELNHLNFTEIVIQMSWRCDE--ILRDCHWQTASRDCCKLFRPRRLPLGYCLAFNELE 228
            .|...:|..:::|..|:::..|::||||  :...|.:.....||||||...:...|.||.||.:.
  Fly   159 ILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMI 223

  Fly   229 KRRGTETGINTGLLLRLLLREGQHAPGNSGLK-------------------GFWLTVVESSVWFG 274
            .....:..:........|...|:    :||||                   |..|.:.|...|..
  Fly   224 SENSRKKHLINQFYPHKLSTAGE----DSGLKFTINASYSFMNNIDALTPFGMNLMIKEPRQWSN 284

  Fly   275 -FPIEVVPHSRTNVAVTAVYHYFDESTLSLPSSWRHCVMDYEEESEHFRTLEGQKYMLENCQAEC 338
             ....:.|.:...|||..:......:|..:....|.|..| :|::..|:. ....|..|||...|
  Fly   285 EMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFD-DEKNPTFQN-TSLTYNRENCLVVC 347

  Fly   339 QQRYLLRYCNCTVDLFYPP-SNYPACRLKDLPCLAAHNHLLQNFEQPGEHPYVHREESGLVCECL 402
            ....:.:.|.|::..|.|| ...|.|.:.|..||..::.:....:...:..|::....|..|:|.
  Fly   348 LHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCP 412

  Fly   403 HNCKSLTLLTDMRKSVQQPWLQ-PNSSAIESMWLNVYFKKPSMLVYKTNLIYTWVDLIVSFGGIC 466
            .||.|  .|.:|..:|::  |. |.:|..:.:...||:.:..|....|.|.||.:||:.:||||.
  Fly   413 DNCNS--RLYEMSLNVRK--LDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYTNIDLLANFGGII 473

  Fly   467 QLCLGCSIISLIEFVFFALYKVPQLYW 493
            .|.:|.|::|.||.:|.    :.:|.|
  Fly   474 SLYIGASVMSFIELLFV----LGKLMW 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk14	NP_609017.2	ASC	45..483	CDD:279230	119/466 (26%)
ppk19	NP_651708.2	ASC	39..489	CDD:279230	119/462 (26%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4697
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I3586
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	1	1.000	-	-		FOG0009975
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.070