DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk14 and egas-4

DIOPT Version :9

Sequence 1:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_501207.2	Gene:	egas-4 / 3564809	WormBaseID:	WBGene00018906	Length:	883	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	61/282 - (21%)
Similarity:	108/282 - (38%)	Gaps:	39/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 LGYCLAFNELE---KRRGTETGINTGLLLRLLLREGQHAP--GNSGLKGFWLTVVESSVWFGFPI 277
            ||.|..||.:.   |.....:|...||.:::.:::.::.|  ..:|:..|..|..|:.......|
Worm   609 LGNCFTFNHMNSSFKYEARSSGYPGGLEMQMNVKQDEYLPWTETAGVMVFTSTKEEAVTSESVRI 673

  Fly   278 EVVPHSRTNVAVTAVYHYFDESTLSLPSSWRHCVMDYEEESEHFRTLEGQKYMLENCQAECQQRY 342
            ...||..:.:|:..|.:|      .|...:..|:....|...::  .:|. |..:.|...|.|..
Worm   674 NTAPHFESRIAINRVDYY------RLGGRYGVCINSVSEVKSYY--YDGD-YTTDGCLRSCYQDV 729

  Fly   343 LLRYCNCTVDLFYP-PSNYPACRLKDLPCLAAHNHLLQNFEQPGEHPYVHREESGLVCECLHNC- 405
            :...|.| :|..|| |::..:|.:....|:   :.|:.:...|...|         .|.|...|
Worm   730 VNGDCGC-MDPRYPMPNDGISCSISQKTCI---DELVDSRGDPSTWP---------ECTCPLPCS 781

  Fly   406 -----KSLTLLTDMRKSVQQPWLQPNSSA-----IESMWLNVYFKKPSMLVYKTNLIYTWVDLIV 460
                 ..|:.|..:.|.|.......|.:|     ::|:.|.:...|...::|...........:.
Worm   782 QTVYTSKLSRLPYVNKIVDCEEAYTNKTACYETFLDSVILRISLPKLDYMIYSETPAMDLTKFMS 846

  Fly   461 SFGGICQLCLGCSIISLIEFVF 482
            ..|||..:.:|.||:|.:|..|
Worm   847 YLGGILSILIGVSIVSFVELFF 868

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk14	NP_609017.2	ASC	45..483	CDD:279230	61/282 (22%)
egas-4	NP_501207.2	EGF	101..131	CDD:278437
		EGF_CA	482..522	CDD:238011
		ASC	<610..869	CDD:279230	60/281 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920