Protein Alignment ppk14 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_609017.2
• Gene: ppk14 / 33887
• FlyBaseID: FBgn0031803
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001258952.1
• Gene: Scnn1b / 20277
• MGIID: 104696
• Length: 638
• Species: Mus musculus
• Alignment Length: 571
• Identity: 108/571 - (18%)
• Similarity: 196/571 - (34%)
• Gaps: 196/571 - (34%)

  Fly    45 YISRSHIHGLYLLFLPSMRRRMRVLW-ALALICACTVLFH--------------VSYLLGDRYHN 94
            |.:.::.||...:.....::  :.:| .|.|:.||.|.:.              ||..:|
Mouse    29 YCNNTNTHGPKRIICEGPKK--KAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMG----- 86

  Fly    95 KQFQTIVAHAHASIHHIAFPVVIICNKNRLNWSRLPEIKSLYNITPSQDELFDRILTAYDGFS-- 157
              |:|           :.||.|.:||.:...:|::..:  |.::....:.:.::||......|
Mouse    87 --FKT-----------MNFPAVTVCNSSPFQYSKVKHL--LKDLDELMEAVLEKILAPEASHSNT 136

  Fly   158 -----FHKFN-----AFD----------SLLGESLDELNHL------------------------ 178
                 |..:|     ..|          :|.|:|.:..|..
Mouse   137 TRTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVC 201

  Fly   179 ---NFT-----------------------EIVIQMSWRCDEILRDCHWQT---ASRDCCKLFRPR 214
               |||                       :.::.|.:..|.|:..|.:.|   :.|:...:|.|
Mouse   202 TLRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYP- 265

  Fly   215 RLPLGYCLAFN-----EL--EKRRGTETGINTGLLLRLLLREGQ--HAPGNSGLKGFWLTVVESS 270
              ..|.|..||     |.  ....|||.|      |:|:|..||  :.|..:...|..|.:.|..
Mouse   266 --DYGNCYIFNWGMTEETLPSANPGTEFG------LKLILDIGQEDYVPFLASTAGARLMLHEQR 322

  Fly   271 VWFGFP------IEVVPHSRTNVAVTAVYHYFDESTLSLPSSWRHCVMDYEEES-EHFRTLEGQK 328
            .   :|      |..:..:.|::.|..      :........:..|.|:..:.: ::..::....
Mouse   323 T---YPFIREEGIYAMAGTETSIGVLV------DKLQRKGEPYSPCTMNGSDVAIKNLYSVYNTT 378

  Fly   329 YMLENCQAECQQRYLLRYCNCTVDLFYPPSNYPACRLKDLPCLAAHNHLLQNFEQPGEHPYVHRE 393
            |.::.|...|.|.:::|.|:|...|:..|.....|..:|.|..|              :.|::.:
Mouse   379 YSIQACLHSCFQDHMIRNCSCGHYLYPLPEGEKYCNNRDFPDWA--------------YCYLNLQ 429

  Fly   394 ESGLVCE-CLHNCK--------SLTL-LTDMRKSVQQPWL-------QPNSSAIE-----SMWLN 436
            .|....| ||..||        .:|: :.|......:.|:       :..||.|.     .:.||
Mouse   430 MSVTQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLN 494

  Fly   437 VYFKKPSMLVYKT-------NLIYTWVDLIVSFGGICQLCLGCSIISLIEF 480
            :||::   ..|:|       |:::    |:.:.||.....:|.|::.||||
Mouse   495 IYFQE---FNYRTIEESPANNIVW----LLSNLGGQFGFWMGGSVLCLIEF 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk14	NP_609017.2	ASC	45..483	CDD:279230	108/571 (19%)
Scnn1b	NP_001258952.1	ENaC	21..621	CDD:273304	108/571 (19%)
		deg-1	29..538	CDD:273309	106/569 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820