Protein Alignment ppk14 and asic-1

DIOPT Version :10

• Sequence 1: NP_609017.2
• Gene: ppk14 / 33887
• FlyBaseID: FBgn0031803
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_491214.3
• Gene: asic-1 / 191422
• WormBaseID: WBGene00022815
• Length: 823
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 93/492 - (18%)
• Similarity: 156/492 - (31%)
• Gaps: 184/492 - (37%)

  Fly    31 KSEIQRAWTLLIDSYISRSHIHGLYLLFLPSMRRRMRVLWALALICACTVLFHVSYLLGDRYHNK 95
            |:.::||..|.:..:...:..||:...::.:..|  |.:|.|..:...:...|.:||:.:|::..
 Worm     3 KNSLKRALELDVVDFAEHTSAHGIPRAYVSTGWR--RYMWLLCFLFCLSCFGHQAYLIVERFNRN 65

  Fly    96 QFQTIVAHAHASIHHIAFPVVIICNKNRLNWSRLPEIKSLYNITPSQDELFDRILTAYDGFSFHK 160
            .   |:.........|.||.|.|||.|....|...|:.::.|..    |.|:..:...||.:..|
 Worm    66 D---IIVGVEIKFEEIKFPAVTICNMNPYKNSAARELGAIRNAI----EAFELAIDKSDGNAHSK 123

  Fly   161 -----------------------FNAFD--------------SLLGESLDELNHLNFTEIVIQMS 188
                                   |.|.|              |.:|::.|:           ::.
 Worm   124 RKKRSANSKMVPIDLLCKEEHGMFTAHDYGHVECTCVTFEDMSKVGDTDDD-----------EIF 177

  Fly   189 WRC----DEILRDCHWQTASRD--CCKLFRPRRLPLGYCLAFNELEK---------RRGTETGIN 238
            |.|    |...:.||....|..  .||.|...      |:: :|:.|         :.||:..|
 Worm   178 WNCHQRKDWTHKICHLAEGSNQLKTCKCFEDT------CVS-DEVTKQLVWPLQLSKNGTKLCI- 234

  Fly   239 TGLLLRLLLREGQHAPGNSG------LKGFWLTVVESSVWFGFPIEVVPHSRTNVAVTAVYHYFD 297
                          :|.:||      .:.|.::...:..|.|                    ..:
 Worm   235 --------------SPESSGPRYCASAQKFQVSTCSNCDWLG--------------------KCE 265

  Fly   298 ESTLSLPSSWRHCVMDYEEESEH----------FRTLEG--QKYMLENCQAECQQRYLLRY---- 346
            ||.          .||.|||.:.          |: ::|  :|......:.:..:|.|.||
 Worm   266 ESD----------DMDLEEEIDSKTCICHHGNCFQ-IKGNVKKRKRRTPERKVHERLLSRYEGLL 319

  Fly   347 -----CNCTVDLFYPPSNYPACRLKDLPCLAAHNHLLQNFEQPGEHPYVHREESGLVCECLHNCK 406
                 ||||               |...|::.            ..|.:..|.|...|.|.:|.|
 Worm   320 AVYSHCNCT---------------KQHGCVST------------SVPDMDLENSNKTCLCFYNKK 357

  Fly   407 SLTLLTDMRKSVQQP-WLQPNSSAIESMWLNVYFKKP 442
            :    ..:....::| |.:...|...:|...||..||
 Worm   358 N----EQIWPCYKEPEWEERKCSRCNTMGDCVYSDKP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk14	NP_609017.2	ASC	45..483	CDD:459966	89/478 (19%)
asic-1	NP_491214.3	deg-1	16..779	CDD:273309	89/479 (19%)