Protein Alignment ppk7 and scnn1b

DIOPT Version :9

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 678
• Identity: 125/678 - (18%)
• Similarity: 222/678 - (32%)
• Gaps: 276/678 - (40%)

  Fly    33 QLALRFGKRTTIHGLDRLLSAKASRWERFVW-LCTFVSAFLGAVY----VCLILSARYNAAHFQT 92
            :|.:.|...|..||..|::  |....:|.:| :.|.|  |.|.|:    |.::....|..:...:
 Frog    30 ELLVWFCDNTNTHGPKRII--KEGPKKRVMWFILTLV--FAGLVFWQWGVLILTYLSYGVSVSLS 90

  Fly    93 VVDSTRFPVYRIPFPVITICNRNRLNWQR-----------LAEAKSRFL---------------- 130
            :...|      :.||.:|:||.|...:.|           :|.|..|..
 Frog    91 IGFKT------MEFPAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQFSSQDQANTFTQSSTN 149

  Fly   131 --------------------ANGSNSAQQELFELIVGTYDDAYFGHFQSF-----------ERLR 164
                                .:.||.....:|:      ::|.:....||           :|.:
 Frog   150 QNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFD------NNAIYSKNNSFRNSSEDQTSYSQRYK 208

  Fly   165 -------NQPTELLNYVNFSQVVD-----------------------FMTWRCNELLAECL---- 195
                   |..|:.: |.||:..:.                       .|.::..:|:..||
 Frog   209 VAMKLCTNNNTQCV-YRNFTSGIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLILTCLFGGQ 272

  Fly   196 ---WRH--HAYDCCEIFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGPMSALSVRV 255
               :|:  ..||         :..|.|:.||  ..:||.     |||     .||.|.:...:::
 Frog   273 PCSYRNFTRIYD---------ADYGNCYIFN--WGQEGE-----DPM-----ASANPGADFGLKL 316

  Fly   256 L--IQPAKHWPGHRETNAMKGIDVMVTEPFVWHNN---PF------FVAANTETTM-----EIEP 304
            :  |:..::.|..:.|.|.:         .:.|..   ||      :....|||::     ::|.
 Frog   317 VLDIEQGEYLPYVQTTAAAR---------LILHQQRSFPFVKDLGIYAMPGTETSIAVLVDQLEH 372

  Fly   305 VIYFYDNDTRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFP 369
            :...|.:.|........|.::.:.::|          |.|::|...|:||.:|:.|.|. |..:|
 Frog   373 MEAPYSSCTVNGSDIPVQNLYAEFNSS----------YSIQSCLRSCYQEQMVQTCGCA-DYQYP 426

  Fly   370 PGQYRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQ--------FQGM--------SC--KCFR 416
                                      .|...|:..|.        :.|:        ||  .|.:
 Frog   427 --------------------------LPNGSEYCSNDKYPDWVPCYYGLRDSVADRESCISLCQQ 465

  Fly   417 NCYSLNYISDVRPAFLPP-------------------DVYAN-NSYVDLDVHFR-FETIMVYR-- 458
            .|....|...:..|..|.                   ::..| |..|.|:::|: |.    ||
 Frog   466 PCNDTQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFN----YRSI 526

  Fly   459 -----TSLVFGWVDLMVSFGGIAGLFLGCSLISGMELAYFL--CIEVPAFGL-----DGLRRRWK 511
                 |::|  |  |:.:.||..|.::|.|::..:|....:  |:.:....|     |..:||.:
 Frog   527 TESEATNVV--W--LLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLAWIKDRRQRRQR 587

  Fly   512 ARRQMDLGVTVPTPTLNFQQTTPSQLME 539
            |:      ...|.||:       |:|:|
 Frog   588 AQ------YADPPPTV-------SELVE 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	112/618 (18%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	125/678 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6952
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4834
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48391
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3633
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.000