Protein Alignment ppk7 and ASIC5

DIOPT Version :9

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_059115.1
• Gene: ASIC5 / 51802
• HGNCID: 17537
• Length: 505
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 111/529 - (20%)
• Similarity: 182/529 - (34%)
• Gaps: 163/529 - (30%)

  Fly    38 FGKRTTIHGLDRLLSAKASRWERFVWLCTF---VSAFLGAVYVCLILSARYNAAHFQTVVDSTRF 99
            |...|:.||:..::..: |:..|.:||...   ||.....:|:.|:     |...:.|.......
Human    41 FAISTSFHGIHNIVQNR-SKIRRVLWLVVVLGSVSLVTWQIYIRLL-----NYFTWPTTTSIEVQ 99

  Fly   100 PVYRIPFPVITICNRNRLNWQRLAEAK-----------SRFL------ANGSNSAQQELFELIVG 147
            .|.::.||.:|.||.||  :|..|.||           |:.|      ||.:.|.:...|.
Human   100 YVEKMEFPAVTFCNLNR--FQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTGSREATDFA---- 158

  Fly   148 TYDDAYFGHFQSFERLRNQPTELLNYVNFSQVVDFMTWRCNELLAECLWRHHAYDCCEIFSKRRS 212
                |...:|...|.:||:..    |:|.|.::|                      ||.|.|..|
Human   159 ----ASHQNFSIVEFIRNKGF----YLNNSTLLD----------------------CEFFGKPCS 193

  Fly   213 ---------KNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGPMSALSVRVLIQPAKHWPGHRE 268
                     :.|.|:.||..||.:.:|          :...:|...:|...|      :.....:
Human   194 PKDFAHVFTEYGNCFTFNHGETLQAKR----------KVSVSGRGLSLLFNV------NQEAFTD 242

  Fly   269 TNAMKGIDVMVTEPFVWHNN---PFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFDD-EH 329
            ..|:..:|..:.  ||.|:.   |.|.....     :.||........|.|::..::..:.: ..
Human   243 NPALGFVDAGII--FVIHSPKKVPQFDGLGL-----LSPVGMHARVTIRQVKTVHQEYPWGECNP 300

  Fly   330 NSKDFKSLQGY-VYMIENCQSECHQEYLVRYCNCTMDLLFPPG--------QYRSC--------R 377
            |.|    ||.: .|....|..||..:::.:.|.|...||  ||        :|.||        .
Human   301 NIK----LQNFSSYSTSGCLKECKAQHIKKQCGCVPFLL--PGYGIECDLQKYFSCVSPVLDHIE 359

  Fly   378 AQDLLCLAEHND-------------LLIYSHNPGEKEFVRNQFQGMSCKCFRNCYSLNYISDVRP 429
            .:||..:..||.             .:.||..|.:|                   :|.|:|   .
Human   360 FKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPSQK-------------------ALKYLS---K 402

  Fly   430 AFLPPDVYANNSYVDLDVHFRFETIMVYRTSLVFGWVDLMVSFGGIAGLFLGCSLISGMELA--- 491
            .......|...:.|.:::::......:.:........:|:...||..|||.|.|||:.:|:.
Human   403 KLNQSRKYIRENLVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYL 467

  Fly   492 ----YFLCI 496
                |::||
Human   468 FTNFYWICI 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	108/524 (21%)
ASIC5	NP_059115.1	ASC	41..466	CDD:279230	108/517 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820