Protein Alignment ppk7 and asic2

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 591
• Identity: 138/591 - (23%)
• Similarity: 225/591 - (38%)
• Gaps: 154/591 - (26%)

  Fly     8 PSKLQQQQQPSRSSRLAQQLAQSSWQLALRFGKRTTIHGLDRLLSAKASRWERFVWLCTFVSAFL 72
            |.:.:.:::.:|.......|:    :|.:....||.:|||..:.|...|...|..|:..|.:. |
Zfish    41 PGQRRARRRHTRPGTPRDDLS----RLTVALLSRTRLHGLRHICSPSNSLSRRAFWMIAFCTC-L 100

  Fly    73 GAVYVCLILSARYN-AAHFQTVVDSTRFP---VYRIPFPVITICNRNRLNWQRLAEAKSRF---- 129
            |     |:||...| ..|:......||..   ...:.||.:||||.|.:....|.::...|
Zfish   101 G-----LLLSWSSNRLLHWLAFPTHTRVHTEWAKELAFPTVTICNNNPVRLYHLTKSDLYFAGHW 160

  Fly   130 ----LANGSNSAQQELFELIVGTYDD--AYFGHFQSFERL-----RNQPTELLNYVNFSQVVDFM 183
                |||  .:|:..:.:|:   .||  .:|.....| ||     |.:.|.|       :.:|.:
Zfish   161 LGLLLAN--RTARPLVLDLL---QDDRRGWFSKLSDF-RLFLPPRRFEGTSL-------EFMDRL 212

  Fly   184 TWRCNELLAECLWRHH---AYDCCEIFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSA 245
            ..:..::|..|.:|..   |::...:|    ::.|.|:.||:  .|||:.::        .|...
Zfish   213 GHQLEDMLLACKYRGEPCGAHNFSTVF----TRYGKCYMFNA--AEEGKTLR--------TTMKG 263

  Fly   246 GPMSALSVRVLIQPAKHWP--GHRETNAMK-GIDVMV----TEPFVWHNNPFFVAANTETTMEIE 303
            |..:.|.:.:.||..::.|  |..|..|.: |:.|.:    ..||| |...|.||...:|.:..:
Zfish   264 GTGNGLEIMLDIQQDEYLPVWGETEETAFEAGVRVQIHSQAEPPFV-HELGFGVAPGFQTFVATQ 327

  Fly   304 PVIYFYDNDTRGVRSDQR---------QCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRY 359
                           :||         :||      |:...|....||.:..|:.||...|:|..
Zfish   328 ---------------EQRLTYLPPPWGECV------SRALDSGLFQVYSVSACRIECETRYIVEN 371

  Fly   360 CNCTMDLLFPPG--------QYRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMSCKCFR 416
            |||.|  ::.||        ||:.|....|..|                    :..:|.:|.|..
Zfish   372 CNCRM--VYMPGDSPYCTPEQYKDCAEPALAAL--------------------SAVEGTNCICRS 414

  Fly   417 NCYSLNYISDVRPAFLP--------------PDVYANNSYVDLDVHF---RFETIMVYRTSLVFG 464
            .|....|..::....:|              .:.|..::.:.|||.|   .:|||...:...|.|
Zfish   415 PCNMTRYNKELSMVKIPSKTSARYLEKKFNRSEKYITDNILVLDVFFEALNYETIEQKKAYEVAG 479

  Fly   465 WVDLMVSFGGIAGLFLGCSLISGMEL---AYFLCIEVPAFGLDGLRRRWKARRQMDLGVTVPTPT 526
               |:...||..|||:|.|:::.:||   ||    ||....|..|..|.:........|:...|.
Zfish   480 ---LLGDIGGQMGLFIGASILTLLELFDYAY----EVVKERLLDLLNREEEEESHGEDVSTCDPV 537

  Fly   527 LNFQQT 532
            :|..::
Zfish   538 VNHSES 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	125/520 (24%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	132/550 (24%)