DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk7 and egas-4

DIOPT Version :9

Sequence 1:	NP_609016.2	Gene:	ppk7 / 33886	FlyBaseID:	FBgn0031802	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_501207.2	Gene:	egas-4 / 3564809	WormBaseID:	WBGene00018906	Length:	883	Species:	Caenorhabditis elegans

Alignment Length:	415	Identity:	86/415 - (20%)
Similarity:	142/415 - (34%)	Gaps:	126/415 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 LFELIVGTYDDAYFGHFQSF-ERLRNQPTELLNYVNF------SQVVDFMTWRCNELLAECLWRH 198
            :::::..||.|......... :.|.|.||.:.:.|.|      .:|...::|...::.   ||..
Worm   528 IYQILNATYGDLGPDKLDEMAQELTNDPTLVRDIVPFLIGGYSLEVRTSLSWTAADMF---LWVA 589

  Fly   199 HAYDCCEIFSKRRSKN----GLCWAFNSLETE-----------EGRRMQL---LDPMWPWRTGSA 245
            :.....::.|.....|    |.|:.||.:.:.           .|..||:   .|...|| |.:|
Worm   590 YEQQLIDLNSNFVQWNDKVLGNCFTFNHMNSSFKYEARSSGYPGGLEMQMNVKQDEYLPW-TETA 653

  Fly   246 GPM----------SALSVRVLIQPAKHWPGHRETN-AMKGIDVMVTEPFVWHNNPFFVAANTETT 299
            |.|          ::.|||:...|      |.|:. |:..:|      :......:.|..|:.:
Worm   654 GVMVFTSTKEEAVTSESVRINTAP------HFESRIAINRVD------YYRLGGRYGVCINSVS- 705

  Fly   300 MEIEPVIYFYDNDTRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTM 364
               |...|:||.|                             |..:.|...|:|:.:...|.| |
Worm   706 ---EVKSYYYDGD-----------------------------YTTDGCLRSCYQDVVNGDCGC-M 737

  Fly   365 DLLFP-PGQYRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMSCKCFRNCYSLNYISDVR 428
            |..:| |....||......|:    |.|:.|..        :......|.|...|....|.|.:
Worm   738 DPRYPMPNDGISCSISQKTCI----DELVDSRG--------DPSTWPECTCPLPCSQTVYTSKL- 789

  Fly   429 PAFLPPDVYANNSYVDLDVHFR-----FETI---------------MVYRTSLVFGWVDLMVSFG 473
             :.||   |. |..||.:..:.     :||.               |:|..:........|...|
Worm   790 -SRLP---YV-NKIVDCEEAYTNKTACYETFLDSVILRISLPKLDYMIYSETPAMDLTKFMSYLG 849

  Fly   474 GIAGLFLGCSLISGMELAYFLCIEV 498
            ||..:.:|.|::|.:|| :||.:::
Worm   850 GILSILIGVSIVSFVEL-FFLFVQL 873

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	84/408 (21%)
egas-4	NP_501207.2	EGF	101..131	CDD:278437
		EGF_CA	482..522	CDD:238011
		ASC	<610..869	CDD:279230	69/324 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820