DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk7 and ppk

DIOPT Version :9

Sequence 1:	NP_609016.2	Gene:	ppk7 / 33886	FlyBaseID:	FBgn0031802	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	565	Identity:	142/565 - (25%)
Similarity:	223/565 - (39%)	Gaps:	110/565 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LALRFGKRTTIHGLDRLLSAKASRWERFVWL-CTFVSAFLGAVYVCLILSARYNAAHFQTVV--D 95
            |.|.:.|.|||||:..:.......:|:..|| .|.:|.:..   |.||............::  |
  Fly    65 LLLEYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFA---VSLIWDTYLKWQESPVILGFD 126

  Fly    96 STRFPVYRIPFPVITIC-------------NRNRLNWQRLAEAKSRFLANGSNSAQQELFELIVG 147
            .|..||::||||.||||             |.:|..|:   |.|..  .|.|:...::|..:.|.
  Fly   127 ETLVPVHKIPFPTITICPEIKMERNVFDYTNVSRQLWE---EYKQN--GNISDLDDEDLARMAVA 186

  Fly   148 TY--DDAYFGHFQSFERLRNQPTELLNYVNFSQVVDFMTWRCNELLAECLWRHHAYDCCEIFSKR 210
            .:  |......|.......|.|.     |:.:|.:..::...||....|.|....|.|.:||...
  Fly   187 MHICDSEVVQRFTPLLSQLNPPN-----VDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDFV 246

  Fly   211 RSKNGLCWAFNSLETEEGRR----MQLLDP------------MWPWR---------TG------S 244
            .:..|:|:.||.|..::..|    :..:||            :.||.         ||      :
  Fly   247 ATDEGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPWNNITGNWSLDTGFVDQGQN 311

  Fly   245 AGPMSAL--SVR----VLIQPAKHWPGHRETNAMKGIDVMVTEPF---VWHNNPFFVAANTETTM 300
            |.|...:  ||:    ..:|..:|...:...:..:|..|.:..|.   :...|...|....|..:
  Fly   312 AYPQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLV 376

  Fly   301 EIEPVIYFYDNDTRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTMD 365
            .:.|......::...:..::|||:||||.:.:.|:|     |...|||:||...|.|..|.|...
  Fly   377 SVLPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRS-----YSQSNCQTECLANYTVSKCGCAKF 436

  Fly   366 LLFPPGQYRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMS--------CKCFRNCYSLN 422
            .:..|.....|..:|:.|.....|.| |:       .::||....|        |.|...|.||.
  Fly   437 WMPKPLGTPVCGLKDINCYTSAQDEL-YT-------LMQNQTMAKSIDESVDITCNCMPACTSLE 493

  Fly   423 YISDVRPAFLPPDV----------YANNSYVD--LDVHFRFETIMVYRTSLVFGWVDLMVSFGGI 475
            |..::..|  ..||          |.:...:.  |.|:|:.......:.:::||...|:.:.|||
  Fly   494 YNFEISRA--KYDVAKTIRAFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGI 556

  Fly   476 AGLFLGCSLISGMELAYFLCIEVPAFGLDGLRRRWKARRQ--MDL 518
            .|||:|.|.:|.:||.||.|:.:.....|  ||:.|.::|  :||
  Fly   557 CGLFMGISCLSFLELIYFFCMRICGSCRD--RRKHKIQQQNSVDL 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	130/532 (24%)
ppk	NP_477232.1	ASC	69..574	CDD:279230	130/532 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.920