DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk7 and ppk13

DIOPT Version :9

Sequence 1:	NP_609016.2	Gene:	ppk7 / 33886	FlyBaseID:	FBgn0031802	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	122/477 - (25%)
Similarity:	202/477 - (42%)	Gaps:	71/477 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KRTTIHGLDRLLSAKASRWERFVW-LCTFVSAFLGAVYVCLILSA-RYNAAHFQTVVDSTRFPVY 102
            |.:|:||...::...||..||..| :|...|.:...:.:...||| ..||..|  ||:|: |..:
  Fly    12 KNSTLHGARFIVDKDASWIERIFWVICLVASWYASWLLIKASLSAFENNAISF--VVESS-FRDW 73

  Fly   103 RIPFPVITICNRNRLNWQRLAE-AKSRFLANGSNSAQQELFELIVGTYDDAYFGHFQSFERLRNQ 166
            ...||.|.:|...  |..|:.| |:..:.|:...:.::.|.|:.....:..:..|..|.|.:
  Fly    74 NTNFPAIIVCESK--NMDRIQEVAEQLWGADHDFTLEEVLSEIAFFRGESYHTVHECSGEEV--- 133

  Fly   167 PTELLNYVNFSQVVDFMTWRCNELLAECLWRHHAYDCCEIFSKRRSKNGLCWAFNSLETEEGRRM 231
             |....|.|||...:.:...|.:.::.|.|.:..::||:.|.:..::.|:|:|.||        |
  Fly   134 -TASCFYSNFSYYAELVRSSCVDSISNCEWNNKPFECCKYFHRMETELGICYAINS--------M 189

  Fly   232 QLLDPMWP----WRTGSAGPMSALSVRVLIQPAKHWPGHRE--TNAMKGIDVMVTEPFVWHNNPF 290
            |...|..|    :....:|| .||.:.:..:......|..|  |......|.:|..|::     .
  Fly   190 QAGKPKMPKLNMYSNRGSGP-GALKMELHTEATVFILGTEEVPTLVTPKTDFLVVGPYI-----S 248

  Fly   291 FVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEY 355
            ||...::..:|       .|.:.|.....||.|.|.|| |..|......|    ..|..:|.::.
  Fly   249 FVRYISKRDIE-------NDEEIRQTSVHQRNCRFADE-NILDVHKFYSY----SACTVQCRKDR 301

  Fly   356 LVRYCNCTMDLLFPPGQYRSCRAQDLLCL-AEHNDLLI----YSHNPGEKEFVRNQFQGMSCKCF 415
            .:..|||:..|......::.|..:.|.|| ..:.||.:    :|...|.|        |:.|.|.
  Fly   302 QMELCNCSSHLSPNSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGRK--------GLVCDCL 358

  Fly   416 RNCYSLNYISDVRPAFLPPDVYANNSYVDLDVHFRFETIMV------YRTSLVFGWVDLMVSFGG 474
            .:|..:    |:...:...:..|.:.    :...|.|..::      |:.:||.|.:||:||.||
  Fly   359 PSCTEV----DITTVYDSKENMAGSQ----NAISRIEVGLIELPTERYKRNLVRGKLDLVVSIGG 415

  Fly   475 IAGLFLGCSLISGMELAYFLCI 496
            ..|||:|.||:|.:|:.|::.|
  Fly   416 TTGLFVGASLLSFVEIFYYITI 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	120/472 (25%)
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	120/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3633
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950