Protein Alignment ppk7 and Asic3

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 112/530 - (21%)
• Similarity: 188/530 - (35%)
• Gaps: 110/530 - (20%)

  Fly     7 PPSKLQQQQQPSRSSRLAQQLAQSSWQLALR-FGKRTTIHGLDRLLSAKASRWERFVWLCTFVSA 70
            |.|.|::.|:...|.              :| |....|:|||..:.........|.:|....:.:
  Rat     3 PRSGLEEAQRRQASD--------------IRVFASSCTMHGLGHIFGPGGLTLRRGLWATAVLLS 53

  Fly    71 FLGAVYVCLILSARYNAAHFQTVVDSTRFPVYRIPFPVITICNRNRLNWQRLAEAKSRFLANGSN 135
            ....:|........|...|.:|.:|...  .:::.||.:|:||.|.|.       :||...|..:
  Rat    54 LAAFLYQVAERVRYYGEFHHKTTLDERE--SHQLTFPAVTLCNINPLR-------RSRLTPNDLH 109

  Fly   136 SAQQELFELIVGTYDDAYFGHFQSFERLRNQPTELLNYV-----NFSQVVDFMTWRCNELLAECL 195
            .|...|..|     |.|   ...::.|...||.....::     :.:|:.........::|.:|
  Rat   110 WAGTALLGL-----DPA---EHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDC- 165

  Fly   196 WRHHAYDC-CEIFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGPMSALSVRVLIQP 259
             |:....| .|.|:...::.|.|:.|||    .....:||      .|...|..:.|.:.:.:|.
  Rat   166 -RYRGQPCGPENFTVIFTRMGQCYTFNS----GAHGAELL------TTPKGGAGNGLEIMLDVQQ 219

  Fly   260 AKH---WPGHRETNAMKGIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVIYFY------DND 312
            .::   |....||....||.|.:   .||.......|..|...:|.:..:.....:      |.:
  Rat   220 EEYLPIWKDMEETPFEVGIRVQIHSQDEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCN 284

  Fly   313 TRGVRSDQRQCVFDDEHNSK--DFKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPPGQYRS 375
            |..:..|.    ||.|.:..  ..:......|.:..|:..|...|:.|.|.|.|  :..||....
  Rat   285 TASLDPDD----FDPEPSDPLGSPRPRPSPPYSLIGCRLACESRYVARKCGCRM--MHMPGNSPV 343

  Fly   376 CRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMSCKCFRNCYSLNYISDVRPAFLPPDVYA-- 438
            |..|      ::.|..    :|.....:|..    :|.|...|.:..|..::....:|....|
  Rat   344 CSPQ------QYKDCA----SPALDAMLRKD----TCVCPNPCATTRYAKELSMVRIPSRASARY 394

  Fly   439 -------NNSYVD-----LDVHF---RFETI---MVYRTSLVFGWVDLMVSFGGIAGLFLGCSLI 485
                   :.||:.     ||:.|   .:|.:   ..|..|      :|:...||..|||:|.||:
  Rat   395 LARKYNRSESYITENVLVLDIFFEALNYEAVEQKAAYEVS------ELLGDIGGQMGLFIGASLL 453

  Fly   486 SGMELAYFLC 495
            :.:|:..:||
  Rat   454 TILEILDYLC 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	104/494 (21%)
Asic3	XP_038963092.1	ENaC	17..547	CDD:273304	107/516 (21%)