Protein Alignment ppk7 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 124/615 - (20%)
• Similarity: 208/615 - (33%)
• Gaps: 176/615 - (28%)

  Fly    15 QQPSRSSRLAQQLAQSSWQLALRFGKRTTIHGLDRLLSAKASR-----WERFVWLCTF-----VS 69
            :||:.......:..:|..:|...|...|||||..||:.:|.:|     | ..:|||||     ..
  Rat    65 RQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFW-AVLWLCTFGMMYWQF 128

  Fly    70 AFLGAVYVCLILSARYNAAHFQTVVDSTRFPVYRIPFPVITICNRNRLNWQRLAEAKSRFLANGS 134
            |.|...|:...:|...|       ::|.     ::.||.:|:|.   ||..|..|.|.. |....
  Rat   129 ALLFEEYLSYPVSLNIN-------LNSD-----KLVFPAVTVCT---LNPYRYTEIKEE-LEELD 177

  Fly   135 NSAQQELFELIVGTYDDAY--------------FGHF-QSFERLRNQPTELLNYV---NFSQV-- 179
            ...:|.||:|.  .|:.:|              .|.| ...:|||..|.......   ..|.|
  Rat   178 RITEQTLFDLY--KYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVRD 240

  Fly   180 ----VDFMTWR-----CNELLAECLWRHHA-----------YDCCEIFSKRRSKNG--------- 215
                ||...|:     ||:..::|.::.::           :....|.|:....:.
  Rat   241 NNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPALEEEALGN 305

  Fly   216 ---LCWAFNSLETEEGRRMQLLDPMWP-------------WRTGSAGPMSALSVRVLIQPAKHWP 264
               .| .||.....:....:...||:.             |.:...|..:.||:.:..:.....|
  Rat   306 FIFTC-RFNQAPCNQANYSKFHHPMYGNCYTFNDKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIP 369

  Fly   265 GHRETNAMKGIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFD 326
               ..:.:.|..|||   .||....:..|.:....||::.:.....    |:.|  .:...|.
  Rat   370 ---LLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKEAL----DSLG--GNYGDCT-- 423

  Fly   327 DEHNSKD--FKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPP------------------- 370
              .|..|  .|:|....|..:.|...|.||.:::.|.|.. :.:|.
  Rat   424 --ENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAY-IFYPKPKGVEFCDYRKQSSWGYCY 485

  Fly   371 ------------GQYRSCRAQDLLCLAEHNDLLIYSHNPGEKEF--VRNQ---FQGMSCKCFRNC 418
                        |.:..||..   |     .::.|..:.|...:  |::|   |:.:|   .:|.
  Rat   486 YKLQGAFSLDSLGCFSKCRKP---C-----SVINYKLSAGYSRWPSVKSQDWIFEMLS---LQNN 539

  Fly   419 YSLNYISDVRPAFLPPDVYANNSYVDLDVHFRFETIMVYRTSLVFGWVDLMVSFGGIAGLFLGCS 483
            |::|              ...|....|::.|:.........|.....|.|:.:.|....|:.|.|
  Rat   540 YTIN--------------NKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSS 590

  Fly   484 LISGMELAYFLCIEVPAFGLDGLRRRWKAR 513
            ::|.:|:|. |..::....|..|.||:::|
  Rat   591 VLSVVEMAE-LIFDLLVITLLMLLRRFRSR 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	114/570 (20%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	122/600 (20%)