Protein Alignment ppk7 and Asic4

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_036020902.1
• Gene: Asic4 / 241118
• MGIID: 2652846
• Length: 586
• Species: Mus musculus
• Alignment Length: 553
• Identity: 128/553 - (23%)
• Similarity: 198/553 - (35%)
• Gaps: 151/553 - (27%)

  Fly    38 FGKRTTIHGLDRLLSAKASRWERFVW---LCTFVSAFLGAVYVCLILSARY-NAAHFQTVVDSTR 98
            |...:|:|||.|..........|.:|   |.|.::|||   |....|:..| ...|...:..:..
Mouse    45 FASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFL---YQAASLARGYLTRPHLVAMDPAAP 106

  Fly    99 FPVYRIPFPVITICNRNRLNWQRLAEAKSRFLAN---------------GSNSAQQELFELIVGT 148
            .||  ..||.:|:||.||.....|::|....|||               |....:.::.:::..|
Mouse   107 APV--AGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRT 169

  Fly   149 YDDAYFGHFQSFERLRNQPTELLNYVNFSQVVDFMTWRCNELLAECLWRHHAYDCCEI--FSKRR 211
                  ||         |..::|...|||                   .||    |..  ||...
Mouse   170 ------GH---------QLADMLKSCNFS-------------------GHH----CSASNFSVVY 196

  Fly   212 SKNGLCWAFNSLETEEGRRMQLLDPM--WPWRTGSAGPMSALSVRVLIQPAKHWPGHRETNAMK- 273
            ::.|.|:.||:            ||.  .|.|.|..|  |.|.:.:.||..::.|..||||...
Mouse   197 TRYGKCYTFNA------------DPQSSLPSRAGGMG--SGLEIMLDIQQEEYLPIWRETNETSF 247

  Fly   274 --GIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFDDEHNSKD 333
              ||.|.:   .||...|...|.|:...:|.:..:.....|.....|      .|..:.|....:
Mouse   248 EAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWG------NCRAESELREPE 306

  Fly   334 FKSLQGY-VYMIENCQSECHQEYLVRYCNCTMDLLFPPGQY------------RSCRAQDLL--- 382
               |||| .|.:..|:..|.:|.:::.|:|.|  :..||.:            |:.|.|..:
Mouse   307 ---LQGYSAYSVSACRLRCEKEAVLQRCHCRM--VHMPGGHLQPVFGATLLSSRTSRRQRCMRTT 366

  Fly   383 C--LAEHNDLLI----YSHNPGE-----------KEFVRNQFQGMS---CKCFRNCYSLNYISDV 427
            |  :..|..:|:    |.|...|           .:...:...|.|   |.|...|....|..::
Mouse   367 CTRIYTHERVLMCMSGYLHMGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEI 431

  Fly   428 RPAFLP--------------PDVYANNSYVDLDVHFRFETIMVYRTSLVFGWVDLMVSFGGIAGL 478
            ....:|              .:.|...:::.|||.|...|.........:|...|:...||..||
Mouse   432 SMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGL 496

  Fly   479 FLGCSLISGMELAYFLCIEVPAFGLDGLRRRWK 511
            |:|.|:::.:|:..:: .||   ..|.|:|.|:
Mouse   497 FIGASILTLLEILDYI-YEV---SWDRLKRVWR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	122/533 (23%)
Asic4	XP_036020902.1	ENaC	40..535	CDD:273304	128/553 (23%)