Protein Alignment ppk7 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001258952.1
• Gene: Scnn1b / 20277
• MGIID: 104696
• Length: 638
• Species: Mus musculus
• Alignment Length: 663
• Identity: 127/663 - (19%)
• Similarity: 213/663 - (32%)
• Gaps: 252/663 - (38%)

  Fly    33 QLALRFGKRTTIHGLDRLL---SAKASRWERFVWLCTFVSAFLGAVYVCLILSARYNAA---HFQ 91
            :|.:.:...|..||..|::   ..|.:.|.....|...:..:...|::...||...:.:   .|:
Mouse    24 ELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFK 88

  Fly    92 TVVDSTRFPVYRIPFPVITICNRNRLNWQR----------LAEAKSRFL----ANGSNSAQQELF 142
            |           :.||.:|:||.:...:.:          |.||....:    |:.||:.:...|
Mouse    89 T-----------MNFPAVTVCNSSPFQYSKVKHLLKDLDELMEAVLEKILAPEASHSNTTRTLNF 142

  Fly   143 EL------------------IVGTYDDAYFGH----------------------------FQSFE 161
            .:                  ::..:.|::...                            .::|.
Mouse   143 TIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTLRNFT 207

  Fly   162 RLRNQPTE--LLNYVN-FSQVV--DF--MTWRCNELLAECLW-----RHHAYDCCEIFSKRRSKN 214
            ......||  :|...| ||||:  |.  |.:..:.::..||:     .|..:  ..||   ....
Mouse   208 SATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNF--TPIF---YPDY 267

  Fly   215 GLCWAFNSLETEE-----------GRRMQLLD----PMWPWRTGSAGPMSALSVRVLIQPAKHWP 264
            |.|:.||...|||           |.:: :||    ...|:...:||      .|:::...:.:|
Mouse   268 GNCYIFNWGMTEETLPSANPGTEFGLKL-ILDIGQEDYVPFLASTAG------ARLMLHEQRTYP 325

  Fly   265 GHRETNAMKGIDVMVTEPFVWHNNPFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQ------- 322
            ..||    :||               :..|.|||::              ||..|:.|
Mouse   326 FIRE----EGI---------------YAMAGTETSI--------------GVLVDKLQRKGEPYS 357

  Fly   323 -CVFDDEHNS-KDFKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPPGQYRSCRAQDLLCLA 385
             |..:....: |:..|:....|.|:.|...|.|::::|.|:|        |.|
Mouse   358 PCTMNGSDVAIKNLYSVYNTTYSIQACLHSCFQDHMIRNCSC--------GHY------------ 402

  Fly   386 EHNDLLIYSHNPGEKEFVRNQF---------------QGMSC--KCFRNCYSLNYISDVRPAFLP 433
                  :|....|||......|               |..:|  .|..:|....|...:..|..|
Mouse   403 ------LYPLPEGEKYCNNRDFPDWAYCYLNLQMSVTQRETCLSMCKESCNDTQYKMTISMADWP 461

  Fly   434 PD--------------------VYANNSYVDLDVHFR-FETIMVYRT---SLVFGWVDLMVSFGG 474
            .:                    ..:....|.|:::|: |.    |||   |.....|.|:.:.||
Mouse   462 SEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFN----YRTIEESPANNIVWLLSNLGG 522

  Fly   475 IAGLFLGCSLISGMELA-------YFLCIEVPAFGLDGLRRRWKARRQMDLGVTVPTPTL----- 527
            ..|.::|.|::..:|..       :...|::.| ...|||||   |.|..  .|.|.||:
Mouse   523 QFGFWMGGSVLCLIEFGEIIIDFIWITIIKLVA-SCKGLRRR---RPQAP--YTGPPPTVAELVE 581

  Fly   528 -----NFQQTTPS 535
                 .||..|.|
Mouse   582 AHTNFGFQPDTTS 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	109/604 (18%)
Scnn1b	NP_001258952.1	ENaC	21..621	CDD:273304	127/663 (19%)
		deg-1	29..538	CDD:273309	108/594 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3633
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850