Protein Alignment ppk7 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 672
• Identity: 136/672 - (20%)
• Similarity: 218/672 - (32%)
• Gaps: 221/672 - (32%)

  Fly    13 QQQQPSRSSRLAQQLAQSSWQLALRFGKRTTIHGLDRLLSAKASR-----WERFVWLCTFVSAFL 72
            :.:||:.......:..:|..:|...|...|||||..||:.:|.:|     | ..:|||||
Mouse    63 EPRQPTEEEEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFW-AVLWLCTF----- 121

  Fly    73 GAVY--VCLILSARYNAAHFQTVVDSTRFPVY--------RIPFPVITICNRNRLNWQRLAEAKS 127
            |.:|  ..|:....::            :||.        ::.||.:|:|.   ||..|..|.|.
Mouse   122 GMMYWQFALLFEEYFS------------YPVSLNINLNSDKLVFPAVTVCT---LNPYRYTEIKE 171

  Fly   128 RFLANGSNSAQQELFELIVGTYDDAYF----GHFQS-----------FERLRNQP---------T 168
            . |.......:|.||:|.  .|:.:|.    |..:|           .:|||..|         :
Mouse   172 D-LEELDRITEQTLFDLY--KYNSSYTRQAGGRRRSTRDLRGALPHPLQRLRTPPPPNPARSARS 233

  Fly   169 ELLNYVNFSQVVDFMTWR-----CNELLAECL--------------WRHHAYDCCE--------- 205
            ...:..:.:..||...|:     ||:..::|.              :|.|..:...
Mouse   234 ASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLPDTSPAL 298

  Fly   206 --------IFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWP-------------WRTGSAGPMS 249
                    ||:.|         ||.....:....|...||:.             |.:...|..:
Mouse   299 EEEALGSFIFTCR---------FNQAPCNQANYSQFHHPMYGNCYTFNNKNNSNLWMSSMPGVNN 354

  Fly   250 ALSVRVLIQPAKHWPGHRETNAMKGIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVIYFYDN 311
            .||:.:..:.....|   ..:.:.|..|||   .||....:..|.|....||::.:.....
Mouse   355 GLSLTLRTEQNDFIP---LLSTVTGARVMVHGQDEPAFMDDGGFNVRPGVETSISMRKEAL---- 412

  Fly   312 DTRGVRSDQRQCVFDDEHNSKD--FKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPP---- 370
            |:.|  .:...|.    .|..|  .|:|....|..:.|...|.||.:::.|.|.. :.:|.
Mouse   413 DSLG--GNYGDCT----ENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAY-IFYPKPKGV 470

  Fly   371 ---------------------------GQYRSCRAQDLLCLAEHNDLLI-YSHNPGEKEFVRNQ- 406
                                       |.:..||..   |...:..|.. ||..|.    |::|
Mouse   471 EFCDYLKQSSWGYCYYKLQAAFSLDSLGCFSKCRKP---CSVTNYKLSAGYSRWPS----VKSQD 528

  Fly   407 --FQGMSCKCFRNCYSLNYISDVRPAFLPPDVYANNSYVDLDVHFRFETIMVYRTSLVFGWVDLM 469
              |:.:|   .:|.|::|              ...|....|::.|:.........|.....|.|:
Mouse   529 WIFEMLS---LQNNYTIN--------------NKRNGVAKLNIFFKELNYKTNSESPSVTMVSLL 576

  Fly   470 VSFGGIAGLFLGCSLISGMELA---YFLCIEVPAFGLDGLRRR-WK----ARRQMDLG------- 519
            .:.|....|:.|.|::|.:|:|   :.|.:......|...|.| |.    ||...::.
Mouse   577 SNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLIMLLHRFRSRYWSPGRGARGAREVASTPASSF 641

  Fly   520 -------VTVPTPTLNFQQTTP 534
                   .|.|.|:|..|.|||
Mouse   642 PSRFCPHPTSPPPSLPQQGTTP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	117/585 (20%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	134/655 (20%)
		deg-1	88..600	CDD:273309	117/582 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820