Protein Alignment ppk7 and asic-1

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_491214.3
• Gene: asic-1 / 191422
• WormBaseID: WBGene00022815
• Length: 823
• Species: Caenorhabditis elegans
• Alignment Length: 873
• Identity: 152/873 - (17%)
• Similarity: 251/873 - (28%)
• Gaps: 438/873 - (50%)

  Fly    27 LAQSSWQLALR-----FGKRTTIHGLDRLLSAKASRWERFVWLCTF---VSAFLGAVYVCLILSA 83
            :.::|.:.||.     |.:.|:.||:.|  :..::.|.|::||..|   :|.|....|   ::..
 Worm     1 MGKNSLKRALELDVVDFAEHTSAHGIPR--AYVSTGWRRYMWLLCFLFCLSCFGHQAY---LIVE 60

  Fly    84 RYNAAHFQTVVDSTRFPVYRIPFPVITICNRNRLNWQRLAEAKSRFLANGSNSAQQEL------- 141
            |:|.   ..::.........|.||.:||||.|..                .|||.:||
 Worm    61 RFNR---NDIIVGVEIKFEEIKFPAVTICNMNPY----------------KNSAARELGAIRNAI 106

  Fly   142 --FELIVGTYDDAYFGHFQSFERLRNQ---PTELL---------------------NYVNFSQVV 180
              |||.:...|..  .|.:..:|..|.   |.:||                     .:.:.|:|.
 Worm   107 EAFELAIDKSDGN--AHSKRKKRSANSKMVPIDLLCKEEHGMFTAHDYGHVECTCVTFEDMSKVG 169

  Fly   181 DF----MTWRCNEL---------LAE--------------------------------------- 193
            |.    :.|.|::.         |||
 Worm   170 DTDDDEIFWNCHQRKDWTHKICHLAEGSNQLKTCKCFEDTCVSDEVTKQLVWPLQLSKNGTKLCI 234

  Fly   194 -----------------------CLWR----------------------HHAYDCCEIFS----- 208
                                   |.|.                      ||. :|.:|..
 Worm   235 SPESSGPRYCASAQKFQVSTCSNCDWLGKCEESDDMDLEEEIDSKTCICHHG-NCFQIKGNVKKR 298

  Fly   209 KRR-------------------------------------------SKNGLCWAFNSLETEEGRR 230
            |||                                           :.|..|..|.:.:.|:
 Worm   299 KRRTPERKVHERLLSRYEGLLAVYSHCNCTKQHGCVSTSVPDMDLENSNKTCLCFYNKKNEQ--- 360

  Fly   231 MQLLDPMWP------W------RTGSAG-------------------PM-------------SAL 251
                  :||      |      |..:.|                   |:             ::|
 Worm   361 ------IWPCYKEPEWEERKCSRCNTMGDCVYSDKPKKQTISCLCATPIKMCVRIDPPQTNDTSL 419

  Fly   252 SVRVL----IQP----------------AKHWPGHRETNAMK---------GIDVMVTE------ 281
            ..||:    |||                |..:.|.::..|::         .:|.:..|
 Worm   420 DDRVVKFWDIQPSTTMSPIVKKKEERDKAYGYTGVKDRIALRAKAMENMIFAVDALTEEEKWKIS 484

  Fly   282 ---------------------PFVWHNNPFFVAA---------NTETT------MEIEPVI---- 306
                                 .||.:.:|.:.|.         ||...      :.:|..:
 Worm   485 YNKSDFIMKCSFNGRECNVKHDFVEYLDPTYGACFTYGQKLGNNTNERSGPAYGLRLEVFVNVTE 549

  Fly   307 YFYDNDTRGVR-----SDQR---------------------------------QCVFDDEHNSKD 333
            |....:..|||     :|::                                 .||  .|..::|
 Worm   550 YLPTTEAAGVRLTVHATDEQPFPDTLGFSAPTGFVSSFGIKLKSMVRLPAPYGDCV--REGKTED 612

  Fly   334 FKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPPGQYR---SCRAQDLLCLAEHNDLLIYSH 395
            |...| ..|..|.||..|.|::|.:.|.|. |..|||  ||   :|...|
 Worm   613 FIYTQ-KAYNTEGCQRSCIQKHLSKTCGCG-DPRFPP--YRESKNCPVDD--------------- 658

  Fly   396 NPGEKEFVRNQFQ---------GMSCK--CFRNCYSLNYISDVRPAFLPPDV------------- 436
             |.::|.::|:..         |.|||  |.::.||::|.:...|| :..|:
 Worm   659 -PYKRECIKNEMHVATRDSKKLGCSCKQPCNQDVYSVSYSASRWPA-IAGDLSGCPLGMAAHHCL 721

  Fly   437 -YANNSYVDLDVHF---RFETIMVYRTSLVFGWVDLMVSFGGIAGLFLGCSLISGMELA-YFLCI 496
             |.......::|:|   .:|:::   .|..:||.:|:..|||..||::|.|:|:..|:| :|..:
 Worm   722 NYKREQGSMIEVYFEQLNYESLL---ESEAYGWSNLLSDFGGQLGLWMGVSVITIGEVACFFFEV 783

  Fly   497 EVPAFGLDGLRRRWKARRQMDLGVTVPT 524
            .:.....:..:|| .||:.....:...|
 Worm   784 FISLISSNRTKRR-PARKSFSSSLRCST 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	143/824 (17%)
asic-1	NP_491214.3	deg-1	16..779	CDD:273309	143/824 (17%)