Protein Alignment ppk7 and unc-105

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001364812.1
• Gene: unc-105 / 174306
• WormBaseID: WBGene00006832
• Length: 974
• Species: Caenorhabditis elegans
• Alignment Length: 824
• Identity: 148/824 - (17%)
• Similarity: 238/824 - (28%)
• Gaps: 352/824 - (42%)

  Fly     7 PPSKLQQQQQPSRSSRLAQQLAQS------------------SW-QLALRFGKRTTIHGLDRLLS 52
            |||..:::....|.....::|:.:                  .| ||...|.|::|.||:....:
 Worm    70 PPSGARKRSHNKRLHDWRRRLSVNPELLRRHGLRNIRMNGHLDWNQLRKSFEKQSTFHGISHAAT 134

  Fly    53 AKASRWERFVWLCTFVSAFLGAVYVCLILSARYNAAHFQTVVDSTRFPVYRIPFPVITICNRNRL 117
            |. .:| |:.|...|....|..:.....|.::|. .:.:||....:|.  ..|||.|||||.|..
 Worm   135 AD-GKW-RWFWYTAFTICLLALLIQIFFLISKYR-QYGKTVDLDLKFE--NAPFPSITICNLNPY 194

  Fly   118 NWQRLAEAKSRFLANGSNSAQQELFELIVGTYD---------DAYFG----------HFQSFERL 163
            .       ||...:|.:..|..|.:...:|:.|         .|..|          ..:...||
 Worm   195 K-------KSAIQSNPNTKAMMEAYSRRIGSGDKTEGIAAALSATGGLHAKVRRAKRKAKGKPRL 252

  Fly   164 RNQPTELLNYVNFSQVVDFMTWRCNELLAECLWRHHAYDCCEIFSKRRSKNGLCWA--------- 219
            |::                   |.::..|:||        |:|......:.|.|:|
 Worm   253 RDR-------------------RYHQAFAQCL--------CDIEQLTGDRKGSCFAAFKGKIEID 290

  Fly   220 ------FNSLETEEGRRMQLLD----PMWP------WR----------TGSAGPMSALSVRVLIQ 258
                  |.:|.|  .|.:..||    .:||      |:          ||.. ||.......|.:
 Worm   291 TNNTAGFMNLHT--SRCLCQLDTVSKALWPCFPYSSWKEKLCSECVDNTGHC-PMRFYKGNELYE 352

  Fly   259 PAKHWPG----HRETN------------------------------------AMKGIDVMVTE-P 282
            ..|....    |:|.|                                    ..|..:|..|| |
 Worm   353 NIKEQVDLCLCHKEYNHCVSTRDDGIILEISPNDELNDLDIGKKIASQLSAQQEKQAEVTTTEAP 417

  Fly   283 FV-------------------WHNNPFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFD-- 326
            .|                   ..|..|.|...:|...  |.:.|..|........:|:.|..|
 Worm   418 TVTQALGFEELTDDIAITSQAQENLMFAVGEMSEKAK--ESMSYELDELVLKCSFNQKDCQMDRD 480

  Fly   327 -----------------------------------------------------------DEH--- 329
                                                                       |:|
 Worm   481 FTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLYANVSEYLPTTEAVGFRITVHDKHIVP 545

  Fly   330 -------------------NSKDFKSLQ-------------------GYVYMIENCQSECHQEYL 356
                               ..|.|..|:                   |:.|.:|.|...|.|:.:
 Worm   546 FPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVI 610

  Fly   357 VRYCNCTMDLLFPPGQ---------------YRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQ 406
            |..|.|. |.::|..:               .|.|.....|.|.|     :||  .|::..:.:
 Worm   611 VEACGCA-DPMYPVAEMFGNNTKPCQAVNMDQRECLRNTTLWLGE-----LYS--KGKEAIIPD- 666

  Fly   407 FQGMSCKCFRNCYSLNY---------------ISDVRPA-FLPPDVYANNS------YVDLDVHF 449
                 |.|.:.|...||               :.:..|. ||..:.|..|:      |.:|:
 Worm   667 -----CYCHQPCQETNYEVTYSSARWPSGSAKVMECLPGDFLCLEKYRKNAAMVQIFYEELN--- 723

  Fly   450 RFETIMVYRTSLVFGWVDLMVSFGGIAGLFLGCSLISGMELAYFLCIEVPAFGLDGLRRRWKARR 514
             :||:   :.|..:....::...||:.||::|.|::|.:|:...:.....|:    :|:| |...
 Worm   724 -YETM---QESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLIVFATQAY----VRKR-KGSI 779

  Fly   515 QMDLGVTVPT--------PTLNFQQTTPSQLMENYIMQLKAEKA 550
            ......:||.        .||:...||.|..:.  :|.:::.|:
 Worm   780 SAQSHHSVPVHRASRVSLNTLHKSSTTQSVKLS--VMDIRSIKS 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	127/707 (18%)
unc-105	NP_001364812.1	deg-1	119..763	CDD:273309	127/708 (18%)