DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk7 and del-10

DIOPT Version :9

Sequence 1:	NP_609016.2	Gene:	ppk7 / 33886	FlyBaseID:	FBgn0031802	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	101/523 - (19%)
Similarity:	187/523 - (35%)	Gaps:	147/523 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFPPSKLQQQQQP--SRSSRLAQQLAQ--SSWQLALRFGKRTTIHGLD----------RLLSA-- 53
            :.|.:..:.:.:|  ||..|:.|..::  |...|....|:|.|:...|          :.|.|
Worm    12 FIPEANQRNENEPAYSRYKRVGQNRSRLNSRASLGSSMGRRITLIETDSGVIEVESDKQFLDAFK 76

  Fly    54 -----------KASRWERFVWLCTFVSAFLGAVYV-CLILSARYNAAHFQTVVDSTRFPVYRIPF 106
                       .||...|.:| |..:.||:..|.| |......|.:....|.::: .:| .:|.|
Worm    77 DANMDAVHHLNAASPVTRGLW-CMIIIAFVILVLVQCYSQIKLYISEPVATNIEA-EYP-SKISF 138

  Fly   107 PVITICNRNRLNWQRLAEAKSRFLANG--SNSAQQELFELIVGTYDDAYFGHFQSFERLRNQPTE 169
            |.:.|||.|:.   ||.     :|..|  .|...:.:...::.|..|..    ..|:.:..:..:
Worm   139 PTVAICNNNQF---RLT-----YLTGGRIMNRRSKSISGSLLSTGHDVE----SVFDTVLRKSWD 191

  Fly   170 LLNYVNFSQVVDFMT----WRCNELLAECLWRHHAYDCCEI--FSKRRSKNGLCWAFNSLETEEG 228
            :       ..|.|:.    |:...:|. |.|.:..  .|::  |....:..|||||.|:
Worm   192 M-------DAVKFLRSAAHWKSRMILG-CTWPNGT--SCKLSDFKAVWTTTGLCWAINT------ 240

  Fly   229 RRMQLLDPMWPWRTGSAGPMSALSVRVLIQP-------AKHWPGHRETNAMKGIDVMV-TEPFVW 285
                  ||..|:....:|....|.:.:.::.       .||:    .|..:.|:.::: .:..:.
Worm   241 ------DPHNPYEVTGSGEGHGLRLLLNVESYERVDACTKHF----RTKTLPGLKILIYNQTDIP 295

  Fly   286 HNNPFFVAANTETTMEIEPVIYFYDNDTRGVRSDQRQCVFDDEHN---SKDFK--------SLQG 339
            .::...|...:..:|:| |....:.:...||     .|:.:::..   |.||.        :|:.
Worm   296 DSSMNGVNVPSGYSMDI-PFKMQHRSKLTGV-----HCIEENDEQIEASTDFNNPENIRTCTLRR 354

  Fly   340 YVYMIEN-CQSECHQEYL-----VRYCNCTMDLLFPPGQYRSCRAQDLLCLAEHNDLLIYSHNPG 398
            |:..:|| |.....:.|.     |:...|.:|      ||..|                     .
Worm   355 YMTEVENSCHCTLRRAYTSNSTDVKMKACNVD------QYFGC---------------------A 392

  Fly   399 EKEFVRNQFQGMSCKCFRNCYSLNYIS---------DVRPAFLPPDVYANNSYV---DLDVHFRF 451
            :|...|.:.:|.:..|...|.|::|.:         ::.||.:......:...|   :||.:..|
Worm   393 QKAMQRIREEGTASTCLPPCKSIDYTAWQDMNRLPQNLMPALIEEQEEDDEDDVEQEELDENVSF 457

  Fly   452 ETI 454
            .|:
Worm   458 STV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:279230	93/486 (19%)
del-10	NP_495302.3	ASC	83..>419	CDD:279230	80/409 (20%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820