Protein Alignment ppk7 and Asic3

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 592
• Identity: 133/592 - (22%)
• Similarity: 215/592 - (36%)
• Gaps: 132/592 - (22%)

  Fly     7 PPSKLQQQQQPSRSSRLAQQLAQSSWQLALR-FGKRTTIHGLDRLLSAKASRWERFVWLCTFVSA 70
            |||.|::.|:...|.              :| |....|:|||..:.........|.:|....:.:
Mouse     3 PPSGLEEAQRRQASD--------------IRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLS 53

  Fly    71 FLGAVYVCLILSARYNAAHFQTVVDSTRFPVYRIPFPVITICNRNRLNWQRLAEAKSRFLANGSN 135
            ....:|........|...|.:|.:|...  .:::.||.:|:||.|.|.       :||...|..:
Mouse    54 LAAFLYQVAERVRYYGEFHHKTTLDERE--SHQLTFPAVTLCNINPLR-------RSRLTPNDLH 109

  Fly   136 SAQQELFELIVGTYDDAYFGHFQSFERLRNQPTELLNYV-----NFSQVVDFMTWRCNELLAECL 195
            .|...|..|     |.|   ...::.|...||.....::     :.:|:.........::|.:|
Mouse   110 WAGTALLGL-----DPA---EHAAYLRALGQPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDC- 165

  Fly   196 WRHHAYDC-CEIFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGPMSALSVRVLIQP 259
             |:....| .|.|:...::.|.|:.|||  ..:|..: |..|     .|.||  :.|.:.:.:|.
Mouse   166 -RYRGQPCGPENFTVIFTRMGQCYTFNS--GAQGAEL-LTTP-----KGGAG--NGLEIMLDVQQ 219

  Fly   260 AKH---WPGHRETNAMKGIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVIYFY------DND 312
            .::   |....||....||.|.:   .||.......|..|...:|.:..:.....:      |.:
Mouse   220 EEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCN 284

  Fly   313 TRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFP-------P 370
            |..|..|     ||.|.:...........|.:..|:..|...|:.|.|.|.| :..|       |
Mouse   285 TASVDPD-----FDPEPSDPLGSPSSSPPYSLIGCRLACESRYVARKCGCRM-MHMPGNSPVCSP 343

  Fly   371 GQYRSCRAQDL-------LCLAEHNDLLIYSHNP-GE----------KEFVRNQFQGMSCKCFRN 417
            .||:.|.:..|       |.:..|:|:   .||| |:          ...:|..    :|.|...
Mouse   344 QQYKDCASPALGKAHLFSLPVPIHSDI---DHNPLGQVLLFLALRPADAMLRKD----TCVCPNP 401

  Fly   418 CYSLNYISDVRPAFLP--------------PDVYANNSYVDLDVHF---RFETI---MVYRTSLV 462
            |.:..|..::....:|              .:.|...:.:.||:.|   .:|.:   ..|..|
Mouse   402 CATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVS-- 464

  Fly   463 FGWVDLMVSFGGIAGLFLGCSLISGMELAYFLCIEVPAFGLDGL--RRRWKARRQMDLGVTVPTP 525
                :|:...||..|||:|.||::.:|:..:|| ||....:.|.  .||...||.   |.|:...
Mouse   465 ----ELLGDIGGQMGLFIGASLLTILEILDYLC-EVFQDRVLGYFWNRRSSQRRS---GNTLLQE 521

  Fly   526 TLNFQQT 532
            .||..:|
Mouse   522 ELNGHRT 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	112/517 (22%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	126/560 (23%)